ETHYL 7-(4-METHYLPHENYL)-7-OXOHEPTANOATE

Base Information

• Chemical Name: ETHYL 7-(4-METHYLPHENYL)-7-OXOHEPTANOATE
• CAS No.: 122115-49-5
• Molecular Formula: C₁₆H₂₂O₃
• Molecular Weight: 262.349
• Mol file: 122115-49-5.mol

Synonyms:ethyl 7-oxo-7-p-tolylheptanoate

Chemical Property of ETHYL 7-(4-METHYLPHENYL)-7-OXOHEPTANOATE

Chemical Property:

• Vapor Pressure: 8.08E-06mmHg at 25°C
• Melting Point: 56-57 °C
• Boiling Point: 374.9±25.0 °C(Predicted)
• Density: 1.023±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl7-(4-methylphenyl)-7-oxoheptanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ETHYL 7-(4-METHYLPHENYL)-7-OXOHEPTANOATE

There total 1 articles about ETHYL 7-(4-METHYLPHENYL)-7-OXOHEPTANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

6-bromo-hexanoic acid ethyl ester (25542-62-5) + 4-methyl-benzoyl chloride (874-60-2) → ethyl 7-oxo-7-p-tolylheptanoate (122115-49-5)

Guidance literature:

6-bromo-hexanoic acid ethyl ester; With magnesium; lithium chloride; zinc(II) chloride; In tetrahydrofuran; at 20 ℃; for 2.5h; Inert atmosphere;

With copper(I) cyanide di(lithium chloride); In tetrahydrofuran; at -30 ℃; Inert atmosphere;

4-methyl-benzoyl chloride; In tetrahydrofuran; at -30 ℃; Inert atmosphere;

DOI:10.1039/c001845g

upstream raw materials:

6-bromo-hexanoic acid ethyl ester

4-methyl-benzoyl chloride

Refernces