Technology Process of 4-methoxyphenyl 3,6-di-O-benzyl-4-O-triethylsilyl-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzoyl-α-D-xylopyranoside
There total 19 articles about 4-methoxyphenyl 3,6-di-O-benzyl-4-O-triethylsilyl-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzoyl-α-D-xylopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,6-di-tert-butyl-4-methylpyridine; methyl trifluoromethanesulfonate;
In
dichloromethane;
at 40 ℃;
for 48h;
Inert atmosphere;
Molecular sieve 4A;
DOI:10.1021/ja208528c
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / Inert atmosphere
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 0 - 20 °C / Inert atmosphere
3: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / Inert atmosphere
4: triethylsilane; trifluoroacetic acid / dichloromethane / 20 h / 0 - 20 °C / Inert atmosphere
5: 2,6-dimethylpyridine / dichloromethane / 96 h / 0 - 20 °C / Inert atmosphere
6: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere; Molecular sieve 4A
7: 2,6-di-tert-butyl-4-methylpyridine; methyl trifluoromethanesulfonate / dichloromethane / 48 h / 40 °C / Inert atmosphere; Molecular sieve 4A
With
2,6-dimethylpyridine; triethylsilane; 2,6-di-tert-butyl-4-methylpyridine; tetrabutyl ammonium fluoride; sodium hydride; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; methyl trifluoromethanesulfonate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja208528c
- Guidance literature:
-
Multi-step reaction with 6 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 0 - 20 °C / Inert atmosphere
2: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / Inert atmosphere
3: triethylsilane; trifluoroacetic acid / dichloromethane / 20 h / 0 - 20 °C / Inert atmosphere
4: 2,6-dimethylpyridine / dichloromethane / 96 h / 0 - 20 °C / Inert atmosphere
5: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere; Molecular sieve 4A
6: 2,6-di-tert-butyl-4-methylpyridine; methyl trifluoromethanesulfonate / dichloromethane / 48 h / 40 °C / Inert atmosphere; Molecular sieve 4A
With
2,6-dimethylpyridine; triethylsilane; 2,6-di-tert-butyl-4-methylpyridine; tetrabutyl ammonium fluoride; sodium hydride; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; methyl trifluoromethanesulfonate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja208528c
