5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Base Information

Chemical Name:5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal
CAS No.:108470-13-9
Molecular Formula:C₁₇H₂₄O₄
Molecular Weight:292.375
Hs Code.:

Synonyms:5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Suppliers and Price of 5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

There total 16 articles about 5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 113957-00-9
1,5(R)-dihydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptene

: 108470-13-9
5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1248/cpb.35.2219

Reference yield:

: 98039-10-2
3-deoxy-1,2,5,6-di-O-isopropylidene-3-C-(4-metoxybenzyloxymethyl)-α-D-allofuranose

: 108470-13-9
5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Guidance literature:: Multi-step reaction with 10 steps

1: 86.5 percent / 2percent H₂SO₄ / methanol / 15 h / Ambient temperature

2: Et₃N/DMAP / CH₂Cl₂ / 19 h / Ambient temperature

3: NaI / butan-2-one / 24 h / Heating

4: 98.5 percent / H₂ / 10percent Pd-C / 0.5 h

5: 70 percent / 4.5 N HCl / tetrahydrofuran / 5.5 h / 50 °C

6: 86 percent / Ca(BH₄)2 / ethanol / 1 h / Ambient temperature

7: 95 percent / NaIO₄ / methanol; H₂O / 1 h / Ambient temperature

8: 90 percent / ethanol / 10 h / 60 °C

9: 86 percent / LiAlH₄ / tetrahydrofuran / 1 h

10: 96 percent / MnO₂ / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; dmap; manganese(IV) oxide; sodium periodate; lithium aluminium tetrahydride; calcium borohydride; sulfuric acid; hydrogen; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; butanone;
DOI:10.1248/cpb.35.2219

Reference yield:

: 86654-47-9
(R)-1-[(3aR,5S,6R,6aR)-6-(4-Methoxy-benzyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol

: 108470-13-9
5(R)-hydroxy-4(R)-(4-methoxybenzyl)oxymethyl-2-methyl-2(E)-heptenal

Guidance literature:: Multi-step reaction with 9 steps

1: Et₃N/DMAP / CH₂Cl₂ / 19 h / Ambient temperature

2: NaI / butan-2-one / 24 h / Heating

3: 98.5 percent / H₂ / 10percent Pd-C / 0.5 h

4: 70 percent / 4.5 N HCl / tetrahydrofuran / 5.5 h / 50 °C

5: 86 percent / Ca(BH₄)2 / ethanol / 1 h / Ambient temperature

6: 95 percent / NaIO₄ / methanol; H₂O / 1 h / Ambient temperature

7: 90 percent / ethanol / 10 h / 60 °C

8: 86 percent / LiAlH₄ / tetrahydrofuran / 1 h

9: 96 percent / MnO₂ / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; dmap; manganese(IV) oxide; sodium periodate; lithium aluminium tetrahydride; calcium borohydride; hydrogen; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; butanone;
DOI:10.1248/cpb.35.2219