Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester,

Base Information

Chemical Name:Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester,
CAS No.:119066-43-2
Molecular Formula:C₆H₁₁NO₃
Molecular Weight:145.158
Hs Code.:
Mol file:119066-43-2.mol

Synonyms:Cyclopropanecarboxylicacid, 1-amino-2-(hydroxymethyl)-, methyl ester, (1R-cis)-

Suppliers and Price of Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester,

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester,

Chemical Property:

PSA：72.55000
LogP:-0.43060

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester,

There total 5 articles about Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, methyl ester, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 118970-47-1,119066-44-3,119066-45-4,119066-46-5
2-Hydroxymethyl-1-((R)-4-phenyl-oxazolidin-3-yl)-cyclopropanecarbonitrile

: 119066-43-2
(1R,2S)-1-Amino-2-hydroxymethyl-cyclopropanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: 1.) H₂; 2.) HCl / 10percent Pd/C / 1.) 3 atm, MeOH, 20 h; 2.) EtOH

With hydrogenchloride; hydrogen; palladium on activated charcoal;
DOI:10.1016/0040-4039(88)85150-5

Reference yield:

: 119066-47-6
(1R,2S)-2-Hydroxymethyl-1-((R)-2-hydroxy-1-phenyl-ethylamino)-cyclopropanecarboxylic acid methyl ester

: 119066-43-2
(1R,2S)-1-Amino-2-hydroxymethyl-cyclopropanecarboxylic acid methyl ester

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; Yield given. Multistep reaction; 1.) 3 atm, MeOH, 20 h; 2.) EtOH;
DOI:10.1016/0040-4039(88)85150-5