(S)-2-(Methoxydiphenylmethyl)pyrrolidine

Base Information

Chemical Name:(S)-2-(Methoxydiphenylmethyl)pyrrolidine
CAS No.:118971-03-2
Molecular Formula:C18H21NO
Molecular Weight:267.371
Hs Code.:2933990090
European Community (EC) Number:634-256-5
Nikkaji Number:J1.055.985E
Wikidata:Q76421868
Mol file:118971-03-2.mol

Synonyms:(S)-2-(Methoxydiphenylmethyl)pyrrolidine;118971-03-2;(2S)-2-[methoxy(diphenyl)methyl]pyrrolidine;(2S)-2-(methoxydiphenylmethyl)pyrrolidine;SCHEMBL2576834;AKOS022179738;DS-3098;D94880;J-003983;(S)-2-(Methoxydiphenylmethyl)pyrrolidine, 95% (HPLC)

Suppliers and Price of (S)-2-(Methoxydiphenylmethyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95% (HPLC)
100mg
$ 141.00

Sigma-Aldrich
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95% (HPLC)
500mg
$ 348.00

Crysdot
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95%
100mg
$ 218.00

Crysdot
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95%
25mg
$ 109.00

Crysdot
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95%
250mg
$ 349.00

Crysdot
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95%
1g
$ 872.00

Chemenu
(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95%
1g
$ 823.00

American Custom Chemicals Corporation
(S)-2-(METHOXYDIPHENYLMETHYL)PYRROLIDINE 95.00%
500MG
$ 1033.87

American Custom Chemicals Corporation
(S)-2-(METHOXYDIPHENYLMETHYL)PYRROLIDINE 95.00%
100MG
$ 668.83

Abosyn
(S)-2-(methoxydiphenylmethyl)pyrrolidine 95+%
0.25g
$ 800.00

Total 30 raw suppliers

Chemical Property of (S)-2-(Methoxydiphenylmethyl)pyrrolidine

Chemical Property:

Appearance/Colour:white to beige crystals or crystalline powder
Vapor Pressure:0mmHg at 25°C
Refractive Index:1.564
Boiling Point:368.677 °C at 760 mmHg
PKA:10.09±0.10(Predicted)
Flash Point:157.824 °C
PSA：21.26000
Density:1.07 g/cm³
LogP:3.65740
Storage Temp.:2-8°C
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:267.162314293
Heavy Atom Count:20
Complexity:274

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-(Methoxydiphenylmethyl)pyrrolidine 95% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(C1CCCN1)(C2=CC=CC=C2)C3=CC=CC=C3
Isomeric SMILES:COC([C@@H]1CCCN1)(C2=CC=CC=C2)C3=CC=CC=C3
Uses (S)-2-(Methoxydiphenylmethyl)pyrrolidine is a diphenylprolinol methyl ether, which can be used as a catalyst to synthesize: Enantioselective ketones via intermolecular asymmetric Michael addition of aldehydes to nonactivated enones. Stereoselective chiral bipyrazolidin-3-one derivatives by dipolar cycloaddition reaction of azomethine imines with α, β-unsaturated aldehydes. Enantioenriched spiro nitrogen heterocycles via asymmetric nucleophilic epoxidation of α-ylideneoxindole esters. Optically active secondary alcohols by asymmetric addition of Et2Zn to various aldehydes.

Technology Process of (S)-2-(Methoxydiphenylmethyl)pyrrolidine

There total 5 articles about (S)-2-(Methoxydiphenylmethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 118970-99-3
(S)-(-)-1-benzyl-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine

: 118971-03-2
(S)-(-)-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Ambient temperature;

Reference yield:

: 955-40-8,172478-10-3
N-benzyl-L-proline ethyl ester

: 118971-03-2
(S)-(-)-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / diethyl ether / 2 h / Heating

2: 86.5 percent / NaH / tetrahydrofuran / -30 deg C to RT, reflux

3: 94 percent / H₂ / 10 percent Pd/C / ethanol / Ambient temperature

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethanol;

Reference yield:

: 118970-95-9
(S)-1-benzyl-2-(hydroxydiphenylmethyl)pyrrolidine

: 118971-03-2
(S)-(-)-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 86.5 percent / NaH / tetrahydrofuran / -30 deg C to RT, reflux

2: 94 percent / H₂ / 10 percent Pd/C / ethanol / Ambient temperature

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; ethanol;