(S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine

Base Information

• Chemical Name: (S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine
• CAS No.: 163814-41-3
• Molecular Formula: C20H22 N2 O3
• Molecular Weight: 338.4
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID70447009
• Nikkaji Number: J1.466.587K,J931.904B
• Wikidata: Q82265783
• Mol file: 163814-41-3.mol

Synonyms:163814-41-3;(S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine;(2S)-2-[methoxy(diphenyl)methyl]-1-[(E)-2-nitroethenyl]pyrrolidine;[S-(E)]-2-(methoxydiphenylmethyl)-1-(2-nitroethenyl)-pyrrolidine;DTXSID70447009;CCYVRDYAEDJRRD-VVLLFNJHSA-N;(2S)-1-[(E)-2-Nitrovinyl]-2-(methoxydiphenylmethyl)pyrrolidine;(2S)-2-(methoxydiphenylmethyl)-1-[(1E)-2-nitroethenyl]pyrrolidine;(2S)-1-(2-Nitrovinyl)-2alpha-(alpha-phenyl-alpha-methoxybenzyl)pyrrolidine;(2S)-2-(Methoxydiphenylmethyl)-1-[(1E)-2-nitroethenyl]-pyrrolidine

Chemical Property of (S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine

Chemical Property:

• PSA: 58.29000
• LogP: 4.25000
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 338.16304257
• Heavy Atom Count: 25
• Complexity: 444

Purity/Quality:

98%min ^*data from raw suppliers

(S,E)-2-(methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(C1CCCN1C=C[N+](=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3
• Isomeric SMILES: COC([C@@H]1CCCN1/C=C/[N+](=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of (S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine

There total 2 articles about (S,E)-2-(Methoxydiphenylmethyl)-1-(2-nitrovinyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.3%

4-[(E)-2-nitrovinyl]morpholine (101419-83-4,18169-20-5) + (S)-(-)-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine (118971-03-2) → (S)-2-methoxydiphenylmethyl-1-(2-nitrovinyl)pyrrolidine (163814-41-3)

Guidance literature:

In methanol; for 5h; Ambient temperature;

DOI:10.1016/S0957-4166(97)00452-7

Reference yield: 70.0%

methanol (67-56-1) + 4-[(E)-2-nitrovinyl]morpholine (101419-83-4,18169-20-5) + (S)-diphenylprolinol (22348-32-9,63401-04-7,112022-88-5,112068-01-6) → (S)-2-methoxydiphenylmethyl-1-(2-nitrovinyl)pyrrolidine (163814-41-3)

Guidance literature:

at 70 ℃;

DOI:10.3987/COM-97-S(N)107

Reference yield: 87.0%

(S)-2-methoxydiphenylmethyl-1-(2-nitrovinyl)pyrrolidine (163814-41-3) + 3-Allyl-1-(4-methoxy-benzyl)-1,3-dihydro-indol-2-one (206064-06-4) → (S)-3-Allyl-1-(4-methoxy-benzyl)-3-((E)-2-nitro-vinyl)-1,3-dihydro-indol-2-one

Guidance literature:

With n-butyllithium; In hexane; toluene; at -40 - 0 ℃; for 4h;

DOI:10.3987/COM-97-S(N)107

upstream raw materials:

4-[(E)-2-nitrovinyl]morpholine

(S)-(-)-2-(1-methoxy-1,1-diphenylmethyl)-pyrrolidine

methanol

(S)-diphenylprolinol

Downstream raw materials:

(S)-1-benzyl-3-(3-methylbut-2-enyl)-3-(2-nitrovinyl)-2-oxindole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 163814-41-3 [S-(E)]-2-(methoxydiphenylmethyl)-1-(2-nitroethenyl)-pyrrolidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send