2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

Base Information

Chemical Name:2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid
CAS No.:118969-27-0
Molecular Formula:C11H9 N3 O2 S2
Molecular Weight:279.343
Hs Code.:2934200090
DSSTox Substance ID:DTXSID60376319
Nikkaji Number:J2.542.661D
Mol file:118969-27-0.mol

Synonyms:118969-27-0;6-Amino-D-luciferin;2-(6-amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid;2-(6-Aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid;4,5-dihydro-2[6-amino-2-benzthiazolyl]-4-thiazole carboxylic acid;6-amino D-Luciferin;SCHEMBL462233;C11H9N3O2S2;DTXSID60376319;HKSJKXOOBAVPKR-UHFFFAOYSA-N;4-Thiazolecarboxylic acid, 2-(6-amino-2-benzothiazolyl)-4,5-dihydro-;FT-0620930;2-(6-Aminobenzothiazole-2-yl)-2-thiazoline-4-carboxylic acid;2-(6-Aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylicacid;4,5-DIHYDRO-2[6-AMINO-2-BENZTHIAZOLYL]-4-THIAZOLECARBOXYLICACID

Suppliers and Price of 2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(6-Aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylicacid 95+%
1g
$ 1112.00

Biosynth Carbosynth
6-Amino-6-deoxyluciferin
10 mg
$ 450.00

Biosynth Carbosynth
6-Amino-6-deoxyluciferin
5 mg
$ 250.00

Biosynth Carbosynth
6-Amino-6-deoxyluciferin
25 mg
$ 1000.00

American Custom Chemicals Corporation
6-AMINO-6-DEOXYLUCIFERIN 95.00%
5MG
$ 499.26

AK Scientific
2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylicacid
10mg
$ 657.00

Total 29 raw suppliers

Chemical Property of 2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

Chemical Property:

Vapor Pressure:5.33E-15mmHg at 25°C
Refractive Index:1.887
Boiling Point:594.9°Cat760mmHg
PKA:3.47±0.20(Predicted)
Flash Point:313.6°C
PSA：142.11000
Density:1.81g/cm³
LogP:1.84190
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:279.01361889
Heavy Atom Count:18
Complexity:391

Purity/Quality:

99% ^*data from raw suppliers

2-(6-Aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)N)C(=O)O

Technology Process of 2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

There total 3 articles about 2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7724-12-1
2-cyano-6-aminobenzothiazole

: 32443-99-5
D-cysteine hydrochloride

: 118969-27-0
2-(6-aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid

Guidance literature:: With potassium carbonate; In methanol; water; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/asia.201601659

Reference yield:

: 2406-90-8
2-chlorobenzothiazol-6-ylamine

: 118969-27-0
2-(6-aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylsulfoxide

2: (i) NaNH₂, liq. NH₃, (ii) /BRN= 1567902/, MeOH

In dimethyl sulfoxide;
DOI:10.1021/ja00961a030