7724-12-1 Usage
Description
6-Amino-2-benzothiazolecarbonitrile is a chemical compound with the molecular formula C8H6N4S. It is a benzothiazole derivative, specifically an aminobenzothiazolecarbonitrile, known for its versatile applications in various industries.
Uses
Used in Pharmaceutical and Agrochemical Industries:
6-Amino-2-benzothiazolecarbonitrile is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to contribute to the development of new drugs and pesticides.
Used in Dye and Pigment Production:
6-Amino-2-benzothiazolecarbonitrile is used as a key intermediate in the production of dyes and pigments, due to its chemical properties that facilitate color creation and stability.
Used in Rubber Chemical Manufacturing:
In the rubber industry, 6-Amino-2-benzothiazolecarbonitrile is used as a component in the manufacturing of rubber chemicals, enhancing the performance and durability of rubber products.
Used as Antioxidants:
6-Amino-2-benzothiazolecarbonitrile is utilized in the creation of antioxidants, which are essential in preventing the degradation of materials and extending their lifespan.
Used in Biologically Active Compounds Synthesis:
6-Amino-2-benzothiazolecarbonitrile is used as a building block in the synthesis of biologically active compounds, playing a crucial role in pharmaceutical research and development for potential therapeutic applications.
Used in Material Science and Organic Synthesis:
6-Amino-2-benzothiazolecarbonitrile may have potential uses in material science and organic synthesis, indicating its broad applicability in creating new materials and advancing chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 7724-12-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,2 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7724-12:
(6*7)+(5*7)+(4*2)+(3*4)+(2*1)+(1*2)=101
101 % 10 = 1
So 7724-12-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5N3S/c9-4-8-11-6-2-1-5(10)3-7(6)12-8/h1-3H,10H2
7724-12-1Relevant articles and documents
Synthesis and evaluation of D-thioluciferin, a bioluminescent 6'-thio analog of Dluciferin
Rylands, Marwaan,Jardine, Anwar
, p. 176 - 189 (2021/03/17)
All known light-emitting firefly-bioluminescent luciferin analogs are either derived from the 6'-hydroxy- and/or 6'-aminoluciferin. We report the synthesis of D-thioluciferin, a 6'-thio analog or isostere of D-luciferin, starting from p-aminothiophenol, using a unique thioacrylate-S-protecting-group strategy. Upon treatment of Dthioluciferin with purified Photinus pyralis (Ppy) luciferase (Luc), a bioluminescence emission with a red-shift λmax relative to D-luciferin was observed. It was also shown that disulphide and sulphide analogs of Dthioluciferin did not produce similar bioluminescences relative to D-thioluciferin when treated with Ppy Luc under standard conditions, thus, providing a foundation for the development of D-thioluciferin based probes based on disulphide reduction and S-dealkylation.
NOVEL CHEMILUMINESCENT SUBSTRATES FOR FACTOR XA
-
Page/Page column 27, (2020/05/21)
The present invention relates to chemiluminescent substrates of formulas (I-3) and (I-4) for blood clotting enzyme Factor Xa. The substrates are particularly useful for assaying coagulation factors and for quantifying an anticoagulant in a sample.
Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole
Hauser, Jacob R.,Beard, Hester A.,Bayana, Mary E.,Jolley, Katherine E.,Warriner, Stuart L.,Bon, Robin S.
, p. 2019 - 2025 (2016/10/05)
2-Cyanobenzothiazoles (CBTs) are useful building blocks for: 1) luciferin derivatives for bioluminescent imaging; and 2) handles for bioorthogonal ligations. A particularly versatile CBT is 6-amino-2-cyanobenzothiazole (ACBT), which has an amine handle for straight-forward derivatisation. Here we present an economical and scalable synthesis of ACBT based on a cyanation catalysed by 1,4-diazabicyclo[2.2.2]octane (DABCO), and discuss its advantages for scale-up over previously reported routes.