6-Chloroquinoline-3-carboxylic acid

Base Information

Chemical Name:6-Chloroquinoline-3-carboxylic acid
CAS No.:118791-14-3
Molecular Formula:C10H6ClNO2
Molecular Weight:207.6131
Hs Code.:2933499090
European Community (EC) Number:808-678-7
DSSTox Substance ID:DTXSID40557846
Wikidata:Q82439886
Mol file:118791-14-3.mol

Synonyms:6-CHLOROQUINOLINE-3-CARBOXYLIC ACID;118791-14-3;6-chloro-3-quinolinecarboxylic acid;MFCD09787826;3-Quinolinecarboxylic acid, 6-chloro-;SCHEMBL2306751;DTXSID40557846;UYQIRJWFRMCAID-UHFFFAOYSA-N;2,3-Difluoro-4-methylbenzylalcohol;AMY13384;6-chloro-quinoline-3-carboxylic acid;AKOS015850438;AB52327;CS-W008667;FS-3690;SY046768;EN300-243389;6-Chloroquinoline-3-carboxylic acid, AldrichCPR;A804097;J-518664

Suppliers and Price of 6-Chloroquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
6-Chloroquinoline-3-carboxylic acid
5 g
$ 1008.00

SynQuest Laboratories
6-Chloroquinoline-3-carboxylic acid
1 g
$ 352.00

Sigma-Aldrich
6-Chloroquinoline-3-carboxylic acid Aldrich
1g
$ 223.00

Labseeker
6-Chloroquinoline-3-carboxylic acid 95
1g
$ 385.00

Chemenu
6-Chloroquinoline-3-carboxylic acid 98%
10g
$ 1384.00

Chemenu
6-Chloroquinoline-3-carboxylic acid 98%
5g
$ 748.00

Chemenu
6-Chloroquinoline-3-carboxylic acid 98%
1g
$ 204.00

Biosynth Carbosynth
6-Chloroquinoline-3-carboxylic acid
500 mg
$ 200.00

Biosynth Carbosynth
6-Chloroquinoline-3-carboxylic acid
250 mg
$ 115.00

Biosynth Carbosynth
6-Chloroquinoline-3-carboxylic acid
100 mg
$ 58.00

Total 35 raw suppliers

Chemical Property of 6-Chloroquinoline-3-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:228 °C(Solv: ethanol (64-17-5))
Refractive Index:1.69
Boiling Point:382.122 °C at 760 mmHg
PKA:2.02±0.30(Predicted)
Flash Point:184.901 °C
PSA：50.19000
Density:1.47 g/cm³
LogP:2.58640
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:207.0087061
Heavy Atom Count:14
Complexity:234

Purity/Quality:

≥99% ^*data from raw suppliers

6-Chloroquinoline-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=C(C=C2C=C1Cl)C(=O)O

Technology Process of 6-Chloroquinoline-3-carboxylic acid

There total 2 articles about 6-Chloroquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 375854-57-2
6-chloroquinoline-3-carboxylic acid ethyl ester

: 3-[1-(6-Chloroquinoline-3-carbonyl)-piperidin-4-yl]-benzylamine di-hydrochloride

: 118791-14-3
6-Chlor-3-chinolincarbonsaeure

Guidance literature:: With sodium hydroxide; In 1,4-dioxane;

Reference yield:

: 40131-09-7
diethyl methoxymethylenemalonate

: 106-47-8
4-chloro-aniline

: 118791-14-3
6-Chlor-3-chinolincarbonsaeure

Guidance literature:: Yield given. Multistep reaction;

Reference yield:

: 118791-14-3
6-Chlor-3-chinolincarbonsaeure

: 118791-36-9
7-Benzyl-10-chlor-3,4-dihydro-4-methyl-2H-1,4-diazepino<6,5-c>chinolin-2,5(7H)-dion

Guidance literature:: Multi-step reaction with 6 steps

1: SOCl₂

3: 78 percent / NH₃

4: 78 percent

5: 68 percent / base

6: 62 percent / chloranil, t-BuOK / CH₂Cl₂

With thionyl chloride; potassium tert-butylate; ammonia; chloranil; In dichloromethane;