2-(4-Chloro-3-methyl-phenoxy)-ethylamine

Base Information

Chemical Name:2-(4-Chloro-3-methyl-phenoxy)-ethylamine
CAS No.:6487-87-2
Molecular Formula:C₉H₁₂ClNO
Molecular Weight:185.653
Hs Code.:
DSSTox Substance ID:DTXSID40390235
Mol file:6487-87-2.mol

Synonyms:6487-87-2;2-(4-Chloro-3-methyl-phenoxy)-ethylamine;2-(4-chloro-3-methylphenoxy)ethanamine;[2-(4-chloro-3-methylphenoxy)ethyl]amine hydrochloride;2-(4-chloro-3-methylphenoxy)ethan-1-amine;SCHEMBL18263344;DTXSID40390235;STK664059;AKOS000204456;CS-0280558;F79998;EN300-1254091;2-(4-chloro-3-methyl-phenoxy)-ethylamine, AldrichCPR

Suppliers and Price of 2-(4-Chloro-3-methyl-phenoxy)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Chloro-3-methylphenoxy)ethanamine
1g
$ 165.00

Matrix Scientific
2-(4-Chloro-3-methyl-phenoxy)-ethylaminehydrochloride
1g
$ 308.00

Matrix Scientific
2-(4-Chloro-3-methyl-phenoxy)-ethylaminehydrochloride
500mg
$ 200.00

Matrix Scientific
2-(4-Chloro-3-methyl-phenoxy)-ethylamine
1g
$ 400.00

Crysdot
2-(4-Chloro-3-methylphenoxy)ethanamine 95+%
1g
$ 374.00

Biosynth Carbosynth
[2-(4-Chloro-3-methylphenoxy)ethyl]amine hydrochloride
250 mg
$ 200.00

Biosynth Carbosynth
[2-(4-Chloro-3-methylphenoxy)ethyl]amine hydrochloride
500 mg
$ 300.00

Biosynth Carbosynth
[2-(4-Chloro-3-methylphenoxy)ethyl]amine hydrochloride
2 g
$ 650.00

Biosynth Carbosynth
[2-(4-Chloro-3-methylphenoxy)ethyl]amine hydrochloride
1 g
$ 400.00

Biosynth Carbosynth
[2-(4-Chloro-3-methylphenoxy)ethyl]amine hydrochloride
5 g
$ 900.00

Total 6 raw suppliers

Chemical Property of 2-(4-Chloro-3-methyl-phenoxy)-ethylamine

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:185.0607417
Heavy Atom Count:12
Complexity:132

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-Chloro-3-methylphenoxy)ethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)OCCN)Cl
Uses 2-(4-Chloro-3-methylphenoxy)ethanamine is a building block for chemical synthesis.

Technology Process of 2-(4-Chloro-3-methyl-phenoxy)-ethylamine

There total 3 articles about 2-(4-Chloro-3-methyl-phenoxy)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: C₁₄H₂₀ClNO₃

: 6487-87-2
4-(2-aminoethoxy)-1-chloro-2-methylbenzene

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.9b00462

Reference yield:

: 59-50-7
4-Chloro-3-methylphenol

: 6487-87-2
4-(2-aminoethoxy)-1-chloro-2-methylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h

1.2: 16 h / 100 °C

2.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.9b00462