4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline

Base Information

Chemical Name:4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline
CAS No.:1601494-72-7
Molecular Formula:C₂₈H₂₈FNO
Molecular Weight:413.535
Hs Code.:

Synonyms:4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline

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Technology Process of 4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline

There total 1 articles about 4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 25287-24-5
4-methoxy-N-(1-p-tolylethyliden)aniline

: 188245-43-4
1-fluoro-4-(n-butylethynyl)benzene

: 1601494-72-7
4-n-butyl-3-(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline

Guidance literature:: With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate monohydrate; In 1,2-dichloro-ethane; at 120 ℃; for 20h; regioselective reaction;
DOI:10.1016/j.tet.2013.10.003