Technology Process of (-)-(2R)-4-(4-carboxyphenyl)-2-methylthiomethyl-4-oxobutanoic acid
There total 5 articles about (-)-(2R)-4-(4-carboxyphenyl)-2-methylthiomethyl-4-oxobutanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Hexadecane; Rhodococcus sp. TA0250;
In
ethanol;
at 28 ℃;
for 72h;
Microbiological reaction;
DOI:10.1271/bbb.62.1048
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80 percent / trioctylammonium chloride; aq. KOH / H2O / 20 °C
2: Mucor circinelloides IFO 4563; sucrose / ethanol; various solvent(s) / 144 h / 28 °C / Microbiological reaction
3: 5 percent / Nocardia canicruria ATCC 31548; glucose / ethanol; various solvent(s) / 96 h / 28 °C / Microbiological reaction
With
potassium hydroxide; D-glucose; Mucor circinelloides IFO 4563; Nocardia canicruria ATCC 31548; tri-n-octylamine hydrochloride; Sucrose;
In
ethanol; water;
1: Elimination / 2: Oxidation / 3: Oxidation;
DOI:10.1271/bbb.62.1048
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Mucor circinelloides IFO 4563; sucrose / ethanol; various solvent(s) / 144 h / 28 °C / Microbiological reaction
2: 5 percent / Nocardia canicruria ATCC 31548; glucose / ethanol; various solvent(s) / 96 h / 28 °C / Microbiological reaction
With
D-glucose; Mucor circinelloides IFO 4563; Nocardia canicruria ATCC 31548; Sucrose;
In
ethanol;
1: Oxidation / 2: Oxidation;
DOI:10.1271/bbb.62.1048