(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Base Information

Chemical Name:(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol
CAS No.:239789-51-6
Molecular Formula:C₂₁H₃₃N₃O₆
Molecular Weight:423.51
Hs Code.:

(R)-N<sup>2</sup>-benzyloxycarbonyl-N<sup>6</sup>-tert-butoxycarbonyl-N<sup>4</sup>-propionyl-4-azalysinol

Synonyms:(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Suppliers and Price of (R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

There total 8 articles about (R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 239789-45-8
benzyl (R)-2,2-dimethyl-4-(2-aza-4-tert-butoxycarbonylamino)butyl-1,3-oxazolidine-3-carboxylate

: 239789-51-6
(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 4 h / 20 °C

2: methanol; H₂O / 3 h / Heating

3: 0.04 g / Na₂CO₃ / dioxane; H₂O / 3 h

With sodium carbonate; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol; dichloromethane; water;
DOI:10.1021/jo010456e

Reference yield:

: 239789-49-2
benzyl (R)-2,2-dimethyl-4-(2-aza-4-tert-butoxycarbonylamino-2-propionyl)butyl-1,3-oxazolidine-3-carboxylate

: 239789-51-6
(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; H₂O / 3 h / Heating

2: 0.04 g / Na₂CO₃ / dioxane; H₂O / 3 h

With sodium carbonate; In 1,4-dioxane; methanol; water;
DOI:10.1021/jo010456e

Reference yield:

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 239789-51-6
(R)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-propionyl-4-azalysinol

Guidance literature:: Multi-step reaction with 7 steps

1: 79 percent / potassium carbonate / dimethylformamide / 4 h / 20 °C

2: 81 percent / TsOH monohydrate / 3 h / Heating

3: 58 percent / DIBALH / toluene / 3 h / -78 °C

4: 35 percent / sodium cyanoborohydride; acetic acid / methanol

5: 59 percent / 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 4 h / 20 °C

6: methanol; H₂O / 3 h / Heating

7: 0.04 g / Na₂CO₃ / dioxane; H₂O / 3 h

With diisobutylaluminium hydride; sodium cyanoborohydride; sodium carbonate; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo010456e