(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Base Information

Chemical Name:(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone
CAS No.:272766-54-8
Molecular Formula:C₁₄H₂₂O₃
Molecular Weight:238.327
Hs Code.:

Synonyms:(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Suppliers and Price of (2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

There total 3 articles about (2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 272766-99-1
(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethyl-5-cyclohexenone

: 272766-54-8
(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1016/S0040-4020(00)00110-1

Reference yield:

: 213833-81-9
(2R,3R,5R,2'R,3a'S,6a'R)-2-(hexahydrofuro[2,3-b]furan-2'-yl)-5-isopropenyl-2,3-dimethylcyclohexanone

: 272766-54-8
(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: O₃ / methanol; CH₂Cl₂ / -78 °C

1.2: 82 percent / FeSO₄*7H₂O; Cu(OAc)2*2H₂O / methanol; CH₂Cl₂ / -78 - 20 °C

2.1: 99 percent / H₂ / Pd/C / ethyl acetate

With hydrogen; ozone; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate; 1.1: ozonolysis / 1.2: Oxidation / 2.1: Hydrogenation;
DOI:10.1016/S0040-4020(00)00110-1

Reference yield:

: 213833-82-0
(+/-)-2-methoxyhexahydrofuro[2,3-b]furan

: 272766-54-8
(2R,3R)-2-[(2R,3aS,6aR)-hexahydrofuro[b]furan-2-yl]-2,3-dimethylcyclohexanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: CuBr*Me₂S; TMSiCl

1.2: 35 percent / TrSbCl₆ / CH₂Cl₂ / -78 °C

2.1: O₃ / methanol; CH₂Cl₂ / -78 °C

2.2: 82 percent / FeSO₄*7H₂O; Cu(OAc)2*2H₂O / methanol; CH₂Cl₂ / -78 - 20 °C

3.1: 99 percent / H₂ / Pd/C / ethyl acetate

With chloro-trimethyl-silane; copper(I) bromide dimethylsulfide complex; hydrogen; ozone; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate; 1.1: Methylation / 1.2: Mukaiyama reaction / 2.1: ozonolysis / 2.2: Oxidation / 3.1: Hydrogenation;
DOI:10.1016/S0040-4020(00)00110-1