3-(Benzyloxy)-4,4-dimethyloxolan-2-one

Base Information

Chemical Name:3-(Benzyloxy)-4,4-dimethyloxolan-2-one
CAS No.:117895-47-3
Molecular Formula:C13H16 O3
Molecular Weight:220.268
Hs Code.:
DSSTox Substance ID:DTXSID50557958
Nikkaji Number:J1.889.060G
Mol file:117895-47-3.mol

Synonyms:117895-47-3;2-Benzyloxy-3,3-dimethyl-butyrolactone;4,4-dimethyl-3-phenylmethoxyoxolan-2-one;DIHYDRO-4,4-DIMETHYL-3-(PHENYLMETHOXY)-2(3H)-FURANONE;3-(Benzyloxy)-4,4-dimethyloxolan-2-one;3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3h)-one;SCHEMBL2906779;DTXSID50557958;AKOS030241325

Suppliers and Price of 3-(Benzyloxy)-4,4-dimethyloxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-BENZYLOXY-3,3-DIMETHYL-BUTYROLACTONE 95.00%
5MG
$ 498.39

Total 2 raw suppliers

Chemical Property of 3-(Benzyloxy)-4,4-dimethyloxolan-2-one

Chemical Property:

Refractive Index:1.529
PSA：35.53000
LogP:2.15480
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:254

Purity/Quality:

99% ^*data from raw suppliers

2-BENZYLOXY-3,3-DIMETHYL-BUTYROLACTONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COC(=O)C1OCC2=CC=CC=C2)C

Technology Process of 3-(Benzyloxy)-4,4-dimethyloxolan-2-one

There total 13 articles about 3-(Benzyloxy)-4,4-dimethyloxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 100-39-0
benzyl bromide

: 79-50-5
pantolactone

: 117895-47-3
3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one

Guidance literature:: With tetra-(n-butyl)ammonium iodide; silver(l) oxide; In dichloromethane; at 20 ℃; for 48h; Darkness;
DOI:10.1021/ol402017x

Reference yield: 97.0%

: 81927-55-1
O-benzyl 2,2,2-trichloroacetimidate

: 79-50-5,599-04-2,5405-40-3,52126-90-6
(S)-pantolactone

: 20374-33-8,97024-23-2,117895-47-3,96089-96-2
(S)-3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one

Guidance literature:: With trifluorormethanesulfonic acid; In hexane; dichloromethane; at 0 - 20 ℃; Inert atmosphere;

Reference yield: 81.0%

: 1377411-56-7
(2S)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoic acid

: 20374-33-8,97024-23-2,117895-47-3,96089-96-2
(S)-3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one

Guidance literature:: (2S)-4-acetoxy-2-(benzyloxy)-3,3-dimethylbutanoic acid; With potassium carbonate; In methanol; at 20 ℃; for 6h;

With hydrogenchloride; In methanol; water; for 1h;
DOI:10.1055/s-0031-1290489