benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Base Information

Chemical Name:benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate
CAS No.:75986-06-0
Molecular Formula:C₂₆H₂₅NO₆
Molecular Weight:447.488
Hs Code.:

Synonyms:benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Suppliers and Price of benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

There total 7 articles about benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 75986-04-8
benzyl α-(2-oxo-3-methylene-1-azetidinyl)-p-benzyloxyphenylacetate

: 75986-06-0
benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Guidance literature:: With N-ethylmorpholine N-oxide; osmium(VIII) oxide; In dichloromethane; water; acetone; tert-butyl alcohol; for 168h;
DOI:10.1016/S0040-4020(01)96430-0

Reference yield:

: 75986-03-7
benzyl N-(2-bromo-2-propenyl)-p-benzyloxyphenylglycinate

: 75986-06-0
benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 62.7 percent / 2 molpercent Pd(OAc)2, 8 molpercent PPh₃, 1.2 mol. equiv. Bu₃N / hexamethylphosphoric acid triamide / 38 h / 80 °C / 3040 Torr

2: 83 percent / OsO₄

With palladium diacetate; osmium(VIII) oxide; tributyl-amine; triphenylphosphine; In N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1039/c39800000770

Reference yield:

: 75986-02-6
α-amino-4-(phenylmethoxy)benzeneacetic acid phenylmethyl ester HCl

: 75986-06-0
benzyl α-(3-hydroxy-3-hydroxymethyl-2-oxo-1-azetidinyl)-p-benzyloxyphenylacetate

Guidance literature:: Multi-step reaction with 3 steps

1: 81.6 percent / K₂CO₃

2: 62.7 percent / 2 molpercent Pd(OAc)2, 8 molpercent PPh₃, 1.2 mol. equiv. Bu₃N / hexamethylphosphoric acid triamide / 38 h / 80 °C / 3040 Torr

3: 83 percent / OsO₄

With palladium diacetate; osmium(VIII) oxide; tributyl-amine; potassium carbonate; triphenylphosphine; In N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1039/c39800000770