1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

Base Information

Chemical Name:1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide
CAS No.:1258948-98-9
Molecular Formula:C₂₄H₁₉ClN₄O₃
Molecular Weight:446.893
Hs Code.:

Synonyms:1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

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Technology Process of 1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

There total 5 articles about 1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.4%

: 1258948-92-3
1-(4-aminobenzoyl)-2-phenyl-1H-indole-5-carbohydrazide

: 79-04-9
chloroacetyl chloride

: 1258948-98-9
1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

Guidance literature:: With triethylamine; In benzene; for 10h; Reflux;
DOI:10.2174/1573406411006040211

Reference yield:

: 1258948-86-5
4-aminophenone-2-phenyl-5-indolecarboxylic acid

: 1258948-98-9
1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 4 h / Reflux

2: hydrazine hydrate / ethanol / 6 h / Reflux

3: triethylamine / benzene / 10 h / Reflux

With thionyl chloride; hydrazine hydrate; triethylamine; In ethanol; benzene;
DOI:10.2174/1573406411006040211

Reference yield:

: C₂₂H₁₅ClN₂O₂

: 1258948-98-9
1-(4-aminobenzoyl)-N'-(1-chlorovinyloxy)-2-phenyl-1H-indole-5-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 6 h / Reflux

2: triethylamine / benzene / 10 h / Reflux

With hydrazine hydrate; triethylamine; In ethanol; benzene;
DOI:10.2174/1573406411006040211