Technology Process of 4,4,5,5-tetramethyl-2-(4-(4-(trifluoromethoxy)phenoxy)phenyl)-1,3,2-dioxaborolane
There total 8 articles about 4,4,5,5-tetramethyl-2-(4-(4-(trifluoromethoxy)phenoxy)phenyl)-1,3,2-dioxaborolane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium acetate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 18h;
Molecular sieve;
DOI:10.1021/jm500147k
- Guidance literature:
-
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate;
In
N,N-dimethyl-formamide;
at 90 ℃;
for 10h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 100 °C
2.1: palladium 10% on activated carbon; sodium tetrahydroborate / methanol / 20 °C
3.1: sulfuric acid / water; 1,2-dimethoxyethane / 0.17 h / 0 °C
3.2: 0.5 h / 0 - 5 °C
4.1: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / N,N-dimethyl-formamide / 10 h / 90 °C / Inert atmosphere
With
sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sulfuric acid; palladium 10% on activated carbon; potassium acetate; potassium carbonate;
In
methanol; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;