2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride

Base Information

• Chemical Name: 2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride
• CAS No.: 942301-96-4
• Molecular Formula: C₁₆H₁₈FNO₂*ClH
• Molecular Weight: 311.784
• Mol file: 942301-96-4.mol

Synonyms:2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride

Chemical Property of 2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride

There total 1 articles about 2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethyl]-carbamic acid tert-butyl ester (942301-95-3) → 2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride (942301-96-4)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃;

Reference yield: 39.0%

2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride (942301-96-4) + bromoacetic acid methyl ester (96-32-2) → [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride (942301-97-5)

Guidance literature:

2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride; bromoacetic acid methyl ester; With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In ethyl acetate;

upstream raw materials:

[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethyl]-carbamic acid tert-butyl ester

Downstream raw materials:

[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride