[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride

Base Information

• Chemical Name: [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride
• CAS No.: 942301-97-5
• Molecular Formula: C₁₉H₂₂FNO₄*ClH
• Molecular Weight: 383.847
• Mol file: 942301-97-5.mol

Synonyms:[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride

Chemical Property of [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride

There total 1 articles about [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride (942301-96-4) + bromoacetic acid methyl ester (96-32-2) → [2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride (942301-97-5)

Guidance literature:

2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride; bromoacetic acid methyl ester; With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In ethyl acetate;

Reference yield: 66.0%

[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride (942301-97-5) + methylamine (74-89-5) → 2-[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-N-methyl-acetamide hydrochloride

Guidance literature:

[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-acetic acid methyl ester hydrochloride; methylamine; With trimethylaluminum; In tetrahydrofuran; n-heptane; toluene; at 0 - 20 ℃;

With hydrogenchloride; In ethyl acetate;

upstream raw materials:

2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamine hydrochloride

bromoacetic acid methyl ester