3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Base Information

Chemical Name:3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol
CAS No.:943345-07-1
Molecular Formula:C₄H₁₁NO₃*C₂₇H₂₁N₃O₅
Molecular Weight:588.617
Hs Code.:

Synonyms:3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Suppliers and Price of 3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

There total 9 articles about 3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 943345-06-0
3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid

: 77-86-1
2-amino-2-hydroxymethyl-1,3-propanediol

: 943345-07-1
3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Guidance literature:: In methanol; dichloromethane; at 20 ℃;

Reference yield:

: 554-84-7
meta-nitrophenol

: 943345-07-1
3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Guidance literature:: Multi-step reaction with 5 steps

1.1: caesium carbonate / acetone / 1 h / 50 °C

2.1: hydrogen / palladium 10% on activated carbon / methanol / 18 h / 20 °C / Inert atmosphere

3.1: 1.5 h / 150 °C

4.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 20 - 50 °C

4.2: Cooling with ice

5.1: dichloromethane; methanol / 20 °C

With water; hydrogen; caesium carbonate; sodium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; dichloromethane; acetone;

Reference yield:

: 81720-19-6
1-methoxycarbonylmethyloxy-3-nitrobenzene

: 943345-07-1
3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid 2-amino-2-hydroxymethyl-1,3-propanediol

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogen / palladium 10% on activated carbon / methanol / 18 h / 20 °C / Inert atmosphere

2.1: 1.5 h / 150 °C

3.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 20 - 50 °C

3.2: Cooling with ice

4.1: dichloromethane; methanol / 20 °C

With water; hydrogen; sodium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; dichloromethane;