(1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

Base Information

• Chemical Name: (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate
• CAS No.: 753503-56-9
• Molecular Formula: C₃₅H₄₂O₁₂
• Molecular Weight: 654.711
• Mol file: 753503-56-9.mol

Synonyms:(1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

Chemical Property of (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

There total 1 articles about (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-Methylene-di[(1R,1'S,6R,6'S)-6-acetoxycyclohept-3-en-1-yl] bis(4-methoxybenzoate) (321146-15-0) → (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate (753503-56-9)

Guidance literature:

With AD-mix-α; methanesulfonamide; In water; acetonitrile; tert-butyl alcohol; for 24h;

DOI:10.1002/hlca.200490136

Reference yield: 99.0%

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride (39637-99-5,20445-33-4) + (1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate (753503-56-9) → (1S,2R,4S,6S)-4-(acetyloxy)-2-{{(4S,6S)-6-(acetyloxy)-4-[(4-methoxybenzoyl)oxy]cyclohept-1-en-1-yl}methyl}-2-hydroxy-6-[(4-methoxybenzoyl)oxy]cycloheptyl (αR)-α-methoxy-α-(trifluoromethyl)benzeneacetate

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 3h;

DOI:10.1002/hlca.200490136

Reference yield: 97.0%

(1S,6S)-6-(acetyloxy)-{{(1R,2S,4S,6S)-6-(acetyloxy)-1,2-dihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate (753503-56-9) → (1S,6S)-6-(hydroxy)-{{(1R,2S,4S,6S)-1,2,6-trihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate (753503-58-1)

Guidance literature:

With magnesium methanolate; In methanol; for 5h;

DOI:10.1002/hlca.200490136

upstream raw materials:

4,4'-Methylene-di[(1R,1'S,6R,6'S)-6-acetoxycyclohept-3-en-1-yl] bis(4-methoxybenzoate)

Downstream raw materials:

(1S,6S)-6-(hydroxy)-{{(1R,2S,4S,6S)-1,2,6-trihydroxy-4-[(4-methoxybenzoyl)oxy]cycloheptyl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

(4S,6S)-tetrahydro-2-hydroxy-6-{3-{(4S,6S)-6-hydroxy-4-[(4-methoxybenzoyl)oxy]cyclohep-1-en-1-yl}-2-oxopropyl}-2H-pyran-4-yl 4-methoxybenzoate

(1S,6S)-6-hydroxy-4-{{(4R,6R)-6-{(2R)-4-hydroxy-2-[(4-methoxybenzoyl)oxy]butyl}-2,2-dimethyl-1,3-dioxan-4-yl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate

(1S,6S)-6-hydroxy-4-{{(4S,6R)-6-{(2R)-4-hydroxy-2-[(4-methoxybenzoyl)oxy]butyl}-2,2-dimethyl-1,3-dioxan-4-yl}methyl}cyclohept-3-en-1-yl 4-methoxybenzoate