N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

Base Information

Chemical Name:N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine
CAS No.:218610-62-9
Molecular Formula:C₁₅H₂₂F₃N₃O
Molecular Weight:317.354
Hs Code.:

N<sub>1</sub>-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

Synonyms:N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

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Technology Process of N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

There total 5 articles about N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 218610-61-8
(2-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-ylamino)ethyl)-carbamic acid tert-butyl ester

: 218610-62-9
N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

Guidance literature:

Reference yield:

: 218610-57-2
1-bromo-2-(2,2,2-trifluoroethoxy)benzene

: 218610-62-9
N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium t-butanolate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / toluene

2: hydrogenchloride / dichloromethane; water; acetic acid

With hydrogenchloride; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In dichloromethane; water; acetic acid; toluene;

Reference yield:

: 95-56-7
2-hydroxybromobenzene

: 218610-62-9
N₁-(1-(2-(2,2,2-Trifluoroethoxy)phenyl)piperidin-4-yl)ethane-1,2-diamine

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydroxide; potassium carbonate / N,N-dimethyl-formamide

2: sodium t-butanolate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / toluene

3: hydrogenchloride / dichloromethane; water; acetic acid

With hydrogenchloride; sodium hydroxide; potassium carbonate; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In dichloromethane; water; acetic acid; N,N-dimethyl-formamide; toluene;