Cyclohexyl (3-chlorophenyl)methanol

Base Information

• Chemical Name: Cyclohexyl (3-chlorophenyl)methanol
• CAS No.: 522654-02-0
• Molecular Formula: C₁₃H₁₇ClO
• Molecular Weight: 224.73
• DSSTox Substance ID: DTXSID901291154
• Nikkaji Number: J1.894.003E

Synonyms:522654-02-0;Cyclohexyl (3-chlorophenyl)methanol;(3-Chlorophenyl)(cyclohexyl)methanol;DTXSID901291154;(3-chlorophenyl)-cyclohexylmethanol;3-Chloro-alpha-cyclohexylbenzenemethanol

Chemical Property of Cyclohexyl (3-chlorophenyl)methanol

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 224.0967929
• Heavy Atom Count: 15
• Complexity: 189

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(CC1)C(C2=CC(=CC=C2)Cl)O

Technology Process of Cyclohexyl (3-chlorophenyl)methanol

There total 3 articles about Cyclohexyl (3-chlorophenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1 ,5-pentanediol (111-29-5) + 1-(m-Chlorophenyl)ethanol (120121-01-9,135145-34-5,6939-95-3) → (3-chlorophenyl)-cyclohexyl methanol (522654-02-0)

Guidance literature:

With potassium tert-butylate; C₁₄H₁₂BrMnN₂O₃S; In tert-Amyl alcohol; at 140 ℃; for 36h; Inert atmosphere;

DOI:10.1021/acscatal.9b05567

Reference yield: 66.0%

Cyclohexyl iodide (626-62-0) + m-Chlorobenzaldehyde (587-04-2) → (3-chlorophenyl)-cyclohexyl methanol (522654-02-0)

Guidance literature:

With copper(l) iodide; sodium oxalate; zinc; indium chloride; at 20 ℃;

DOI:10.1021/ja029649p

Reference yield:

cyclohexylmagnesiumchloride (931-51-1) + m-Chlorobenzaldehyde (587-04-2) → (3-chlorophenyl)-cyclohexyl methanol (522654-02-0)

Guidance literature:

In diethyl ether; at -78 - 25 ℃;

DOI:10.1016/j.ejmech.2005.04.016

upstream raw materials:

Cyclohexyl iodide

m-Chlorobenzaldehyde

cyclohexylmagnesiumchloride

1 ,5-pentanediol

Downstream raw materials:

(3-chlorophenyl)(cyclohexyl)methanone

3-(3-chloro-phenyl)-3-cyclohexyl-3-hydroxy-1-piperidin-1-yl-propan-1-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 522654-02-0 (3-chlorophenyl)-cyclohexyl methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send