(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Base Information

Chemical Name:(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane
CAS No.:187100-59-0
Molecular Formula:C₄₄H₈₇NO₆SSi₃
Molecular Weight:842.5
Hs Code.:

Synonyms:(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Suppliers and Price of (2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

There total 12 articles about (2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 187100-57-8
(2S,3R,15R,16R,4E)-1,3,15-Tris-tert-butyldimethylsilyloxy-16-methyl-2-p-tolylsulfonylaminooctadec-4-ene

: 187100-59-0
(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

: N-((1S,2S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-2-{(2S,3R)-3-[(10R,11R)-10-(tert-butyl-dimethyl-silanyloxy)-11-methyl-tridecyl]-oxiranyl}-ethyl)-4-methyl-benzenesulfonamide

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In hexane; Ambient temperature;

Reference yield:

: 187100-52-3
(12R,13R)-13-Methylpentadec-1-yn-12-ol

: 187100-59-0
(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Guidance literature:: Multi-step reaction with 6 steps

1: 89 percent / imidazole / dimethylformamide / Ambient temperature

2: 83 percent / BuLi / tetrahydrofuran; hexane

3: Li, EtNH₂ / tetrahydrofuran

4: 83 percent / 2,6-dimethylpyridine / CH₂Cl₂ / Ambient temperature

5: 86 percent / pyridine / Ambient temperature

6: 42 percent / 80percent m-CPBA, NaHCO₃ / hexane / Ambient temperature

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; n-butyllithium; lithium; sodium hydrogencarbonate; ethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 187100-54-5
tert-Butyl (4S)-4-<(1'R,13'R,14'R)-13'-tert-butyldimethylsilyloxy-1'-hydroxy-14'-methylhexadec-2'-ynyl>-2,2-dimethyloxazolidine-3-carboxylate

: 187100-59-0
(2S,3S,4R,5S,15R,16R)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane

Guidance literature:: Multi-step reaction with 4 steps

1: Li, EtNH₂ / tetrahydrofuran

2: 83 percent / 2,6-dimethylpyridine / CH₂Cl₂ / Ambient temperature

3: 86 percent / pyridine / Ambient temperature

4: 42 percent / 80percent m-CPBA, NaHCO₃ / hexane / Ambient temperature

With pyridine; 2,6-dimethylpyridine; lithium; sodium hydrogencarbonate; ethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;