Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-

Base Information

Chemical Name:Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-
CAS No.:1312603-38-5
Molecular Formula:C₁₄H₁₈N₂O₄
Molecular Weight:278.308
Hs Code.:
DSSTox Substance ID:DTXSID501188139

Synonyms:DTXSID501188139;Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-;1312603-38-5

Suppliers and Price of Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:278.12665706
Heavy Atom Count:20
Complexity:326

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CCOCC1=C(C=CC(=C1)[N+](=O)[O-])N2CCOCC2

Technology Process of Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]-

There total 3 articles about Morpholine, 4-[4-nitro-2-[(2-propen-1-yloxy)methyl]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 300665-25-2
(2-morpholin-4-yl-5-nitrophenyl)methanol

: 106-95-6
allyl bromide

: 1312603-38-5
4-(2-allyloxymethyl-4-nitrophenyl)morpholine

Guidance literature:: With tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; at 20 ℃; for 12h;
DOI:10.1021/jm200326p

Reference yield:

: 30742-62-2
2-(N-morpholinyl)-5-nitrobenzaldehyde

: 1312603-38-5
4-(2-allyloxymethyl-4-nitrophenyl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C

2: tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide / 12 h / 20 °C

With sodium tetrahydroborate; tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; In tetrahydrofuran;
DOI:10.1021/jm200326p

Reference yield:

: 6361-21-3
2-chloro-5-nitrobenzaldehyde

: 1312603-38-5
4-(2-allyloxymethyl-4-nitrophenyl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 90 °C

2: sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C

3: tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide / 12 h / 20 °C

With sodium tetrahydroborate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; potassium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm200326p