(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Base Information

Chemical Name:(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole
CAS No.:1415010-43-3
Molecular Formula:C₂₆H₃₈N₂O₅S
Molecular Weight:490.664
Hs Code.:

Synonyms:(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Suppliers and Price of (3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

There total 19 articles about (3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1415010-39-7
(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-(trimethylsilyloxy)perhydro-1H-benzo[e]indole

: 1415010-43-3
(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.0833333h;
DOI:10.1021/ol302880x

Reference yield:

: 1415010-38-6
2-(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3-[(2-nitrobenzenesulfonyl)-9b-(trimethylsilyloxy)perhydro-1H-benzo[e]indol-3a-yl]acetaldehyde

: 1415010-43-3
(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 10 h / 0 - 20 °C / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 20 °C

With n-butyllithium; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane;
DOI:10.1021/ol302880x

Reference yield:

: 1415010-31-9
(3aS,5aS,9aS,9bR)-3a-allyl-6,6,9a-trimethyl-3-(2-nitrobenzenesulfonyl)-9b-(trimethylsilyloxy)perhydro-1H-benzo[e]indole

: 1415010-43-3
(3aS,5aS,9aS,9bR)-6,6,9a-trimethyl-3a-(3-methylbut-2-enyl)-3-(2-nitrobenzenesulfonyl)-9b-hydroxyperhydro-1H-benzo[e]indole

Guidance literature:: Multi-step reaction with 4 steps

1.1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetonitrile / 17 h / 20 °C / Inert atmosphere

2.1: sodium periodate / tetrahydrofuran; water / 2 h / 20 °C

3.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3.2: 10 h / 0 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 20 °C

With sodium periodate; osmium(VIII) oxide; n-butyllithium; tetrabutyl ammonium fluoride; 4-methylmorpholine N-oxide; In tetrahydrofuran; hexane; water; acetonitrile;
DOI:10.1021/ol302880x