1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Base Information

Chemical Name:1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate
CAS No.:732277-69-9
Molecular Formula:C₂₂H₂₁N₅O₇S
Molecular Weight:499.504
Hs Code.:

Synonyms:1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Suppliers and Price of 1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

There total 3 articles about 1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 732277-68-8
1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol

: 124-63-0
methanesulfonyl chloride

: 732277-69-9
1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3.33333h;

Reference yield:

: (+/-)-7-methyl-5-(4-nitrophenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isochromen-6-ylium perchlorate

: 732277-69-9
1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / 2 h / Heating / reflux

2: triethylamine / dichloromethane / 3.33 h / 0 - 20 °C

With triethylamine; In dichloromethane; isopropyl alcohol;

Reference yield:

: 923272-76-8
(5RS,7S)-7.8-dihydro-7-methyl-5-(4-nitrophenyl)-5H-1,3-dioxolo[4,5-G][2]benzopyran-5-ol

: 732277-69-9
1-{6-[(4-nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol mesylate

Guidance literature:: Multi-step reaction with 3 steps

1: perchloric acid / ethyl acetate / 1 h / Heating / reflux

2: isopropyl alcohol / 2 h / Heating / reflux

3: triethylamine / dichloromethane / 3.33 h / 0 - 20 °C

With perchloric acid; triethylamine; In dichloromethane; ethyl acetate; isopropyl alcohol;