4-Morpholinobutane-1-sulfonic acid

Base Information

• Chemical Name: 4-Morpholinobutane-1-sulfonic acid
• CAS No.: 115724-21-5
• Molecular Formula: C₈H₁₇NO₄S
• Molecular Weight: 223.293
• European Community (EC) Number: 627-157-3
• DSSTox Substance ID: DTXSID50394906
• Nikkaji Number: J2.851.715G
• Mol file: 115724-21-5.mol

Synonyms:MOBS;115724-21-5;4-Morpholinobutane-1-sulfonic acid;4-morpholin-4-ylbutane-1-sulfonic Acid;4-(MORPHOLIN-4-YL)BUTANE-1-SULFONIC ACID;4-morpholin-4-ium-4-ylbutane-1-sulfonate;4-(N-Morpholino)butanesulfonic acid;4-Morpholinebutanesulfonic acid;SCHEMBL126113;MOBS, >=99% (titration);DTXSID50394906;4-Morpholinobutane-1-sulfonicacid;VTOWJTPBPWTSMK-UHFFFAOYSA-N;MFCD00674916;HY-W127629;4-Morpholin4-yl-butane-1-sulfonic acid;4-morpholin-4-yl-butane-1-sulfonic acid;AS-60541;CS-0185830;A893828;J-003320

Chemical Property of 4-Morpholinobutane-1-sulfonic acid

Chemical Property:

• PSA: 75.22000
• LogP: 1.00530
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Water Solubility.: Soluble in water.
• XLogP3: -2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 223.08782920
• Heavy Atom Count: 14
• Complexity: 241

Purity/Quality:

99%, ^*data from raw suppliers

MOBS ≥99% (titration) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CCCCS(=O)(=O)O
• Uses: MOPS is frequently used as a buffering agent in biology and biochemistry. It used widely for polyacrylamide gel electrophoresis. Usage above 20 mM in mammalian cell culture work is not recommended.

Technology Process of 4-Morpholinobutane-1-sulfonic acid

There total 2 articles about 4-Morpholinobutane-1-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

morpholine (110-91-8,99108-56-2) + 1,4-butane sultone (1633-83-6) → 4-(N-morpholino)butanesulfonic acid (115724-21-5)

Guidance literature:

In ethanol; at 80 ℃; for 5h;

DOI:10.14233/ajchem.2015.17494

Reference yield:

morpholine (110-91-8,99108-56-2) + 1,4-butane → 4-(N-morpholino)butanesulfonic acid (115724-21-5)

Guidance literature:

In isopropyl alcohol;

upstream raw materials:

morpholine

1,4-butane sultone