CH₄O₃S*C₁₄H₁₄ClFN₂O₂S

Base Information

• Chemical Name: CH₄O₃S*C₁₄H₁₄ClFN₂O₂S
• CAS No.: 1170219-90-5
• Molecular Formula: CH₄O₃S*C₁₄H₁₄ClFN₂O₂S
• Molecular Weight: 424.902
• Mol file: 1170219-90-5.mol

Synonyms:CH₄O₃S*C₁₄H₁₄ClFN₂O₂S

Chemical Property of CH₄O₃S*C₁₄H₁₄ClFN₂O₂S

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of CH₄O₃S*C₁₄H₁₄ClFN₂O₂S

There total 1 articles about CH₄O₃S*C₁₄H₁₄ClFN₂O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H13FN2O2S (1174743-98-6) + methanesulfonic acid (75-75-2,98527-29-8) → CH4O3S*C14H14ClFN2O2S (1170219-90-5)

Guidance literature:

C₁₀H₁₃FN₂O₂S; 1-Chloro-4-(chloromethyl)benzene; With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; water; at 50 ℃; for 5h;

methanesulfonic acid; In tetrahydrofuran; at 50 ℃; for 0.5h;

Reference yield:

C6H15N*C7H8O3 (1206547-75-2) + CH4O3S*C14H14ClFN2O2S (1170219-90-5) → [4-(4-chloro-benzyl)-7-fluoro-5-methanesulfonyl-1,4-dihydro-2H-cyclopenta[b]indol-3-ylidene]-acetic acid (866215-99-8)

Guidance literature:

C₆H₁₅N*C₇H₈O₃; CH₄O₃S*C₁₄H₁₄ClFN₂O₂S; In propionic acid; at 20 - 40 ℃; for 3h;

With methanesulfonic acid; In propionic acid; at 50 - 60 ℃; for 1.05 - 1.08333h; Product distribution / selectivity;

Reference yield:

CH4O3S*C14H14ClFN2O2S (1170219-90-5) + (2E)-(2-oxocyclopentylidene)acetic acid → [4-(4-chloro-benzyl)-7-fluoro-5-methanesulfonyl-1,4-dihydro-2H-cyclopenta[b]indol-3-ylidene]-acetic acid (866215-99-8)

Guidance literature:

In tert-butyl methyl ether; acetonitrile; at 20 - 55 ℃; for 24h; Product distribution / selectivity;

upstream raw materials:

C₁₀H₁₃FN₂O₂S

methanesulfonic acid

Downstream raw materials:

[4-(4-chloro-benzyl)-7-fluoro-5-methanesulfonyl-1,4-dihydro-2H-cyclopenta[b]indol-3-ylidene]-acetic acid