C₂₈H₂₉Cl₃O₅

Base Information

• Chemical Name: C₂₈H₂₉Cl₃O₅
• CAS No.: 1338567-54-6
• Molecular Formula: C₂₈H₂₉Cl₃O₅
• Molecular Weight: 551.894
• Mol file: 1338567-54-6.mol

Synonyms:C₂₈H₂₉Cl₃O₅

Chemical Property of C₂₈H₂₉Cl₃O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₈H₂₉Cl₃O₅

There total 3 articles about C₂₈H₂₉Cl₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

benzyl bromide (100-39-0) + 2,2,2-trichloroethyl D-arabinopyranoside → C28H29Cl3O5 (1338567-54-6) + C28H28Cl2O5 + 1,2-O-(2,2-dichloroethylidene) 3,4-di-O-benzyl-D-arabinopyranoside

Guidance literature:

2,2,2-trichloroethyl D-arabinopyranoside; With sodium hydride; In N,N-dimethyl-formamide; for 2h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; Overall yield = 76 percent; Overall yield = 3.15 g; Inert atmosphere;

DOI:10.1039/d1ob01467f

Reference yield:

2,2,2-trichloroethyl 2,3,4-tris-O-acetyl-D-arabinopyranoside → C28H29Cl3O5 (1338567-54-6) + C28H28Cl2O5 + 1,2-O-(2,2-dichloroethylidene) 3,4-di-O-benzyl-D-arabinopyranoside

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium methylate; methanol / 3 h / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide / 2 h / Inert atmosphere

2.2: Inert atmosphere

With methanol; sodium methylate; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1039/d1ob01467f

Reference yield:

(3S,4R,5R)-tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (108646-05-5) → C28H29Cl3O5 (1338567-54-6) + C28H28Cl2O5 + 1,2-O-(2,2-dichloroethylidene) 3,4-di-O-benzyl-D-arabinopyranoside

Guidance literature:

Multi-step reaction with 3 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 24 h / Reflux

2.1: sodium methylate; methanol / 3 h / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide / 2 h / Inert atmosphere

3.2: Inert atmosphere

With methanol; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/d1ob01467f

upstream raw materials:

benzyl bromide

(3S,4R,5R)-tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Downstream raw materials:

2.3.4-Tri-O-benzyl-β-D-arabinopyranose

Refernces