(R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

Base Information

Chemical Name:(R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester
CAS No.:249278-42-0
Molecular Formula:C₂₈H₃₈N₂O₃
Molecular Weight:450.621
Hs Code.:

Synonyms:(R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

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Chemical Property of (R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

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Technology Process of (R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

There total 3 articles about (R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73674-09-6
8-bromo-n-octanoyl chloride

: 249278-42-0
(R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dibutyl ether / 3 h / Heating

1.2: dibutyl ether / 3 h / Heating

2.1: K₂CO₃ / acetone / 8 h / Heating

With sodium hydride; potassium carbonate; In dibutyl ether; acetone; 1.1: Metallation / 1.2: Acylation / 2.1: Condensation;
DOI:10.1021/jm980492e

Reference yield:

: 122-39-4
diphenylamine

: 249278-42-0
(R)-1-(8-(diphenylamino)-8-oxo-1-octyl)-3-piperidinecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dibutyl ether / 3 h / Heating

1.2: dibutyl ether / 3 h / Heating

2.1: K₂CO₃ / acetone / 8 h / Heating

With sodium hydride; potassium carbonate; In dibutyl ether; acetone; 1.1: Metallation / 1.2: Acylation / 2.1: Condensation;
DOI:10.1021/jm980492e