1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene

Base Information

• Chemical Name: 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene
• CAS No.: 365572-07-2
• Molecular Formula: C₁₁H₁₄BrClO₂
• Molecular Weight: 293.588
• Mol file: 365572-07-2.mol

Synonyms:1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene

Chemical Property of 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene

There total 3 articles about 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-bromo-4-methoxy-5-(1-methylethoxy)benzenemethanol (365572-06-1) → 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene (365572-07-2)

Guidance literature:

With thionyl chloride; In dichloromethane; at 20 ℃; for 1.5h;

Reference yield:

2-bromoisovanillin (2973-59-3) → 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene (365572-07-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / K₂CO₃ / acetonitrile / 48 h / 60 °C

2: 95 percent / sodium borohydride / ethanol / 1 h / 22 °C

3: 95 percent / thionyl chloride / CH₂Cl₂ / 1.5 h / 20 °C

With sodium tetrahydroborate; thionyl chloride; potassium carbonate; In ethanol; dichloromethane; acetonitrile;

Reference yield:

2-bromo-4-methoxy-5-(1-methylethoxy)benzaldehyde (56517-32-9) → 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene (365572-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sodium borohydride / ethanol / 1 h / 22 °C

2: 95 percent / thionyl chloride / CH₂Cl₂ / 1.5 h / 20 °C

With sodium tetrahydroborate; thionyl chloride; In ethanol; dichloromethane;

upstream raw materials:

2-bromo-4-methoxy-5-(1-methylethoxy)benzenemethanol

2-bromoisovanillin

2-bromo-4-methoxy-5-(1-methylethoxy)benzaldehyde

Downstream raw materials:

1-bromo-5-methoxy-4-(1-methylethoxy)-2-[[[2-[4-(1-ethylethoxy)phenyl]ethyl]thio]methyl]benzene

2-bromo-4-methoxy-5-(1-methylethoxy)benzeneacetonitrile

2-[[2-bromo-4-methoxy-5-(1-methylethoxy)phenyl]methyl]-2-[[4-(1-methylethoxy)phenyl]methyl]propanedioic acid dimethyl ester

2-[2-bromo-4-methoxy-5-(1-methylethoxy)phenylmethyl]-2-[2-[4-(1-methylethoxy)-phenyl]ethyl]propanediacid dimethyl ester