56517-32-9

Upstream product

• 34123-66-5 O-isopropylisovanillin 
• 621-59-0 isovanillin 
• 2973-59-3 2-bromoisovanillin 
• 75-26-3 isopropyl bromide 

Downstream Products

• 365572-06-1 2-bromo-4-methoxy-5-(1-methylethoxy)benzenemethanol 
• 475161-26-3 2-bromo-5-isopropoxy-4-methoxyphenyl-[2-(4-isopropoxybenzyl)]-phenylmethanol 
• 445483-23-8 benzyl 2-formyl-4-isopropoxy-5-methoxyphenyl sulfide 
• 365572-07-2 1-bromo-2-(chloromethyl)-5-methoxy-4-(1-methylethoxy)benzene 
• 380375-83-7 4-bromo-5-[[2-(4-hydroxyphenyl)ethylsulfonyl]methyl]-2-methoxyphenol 
• 380375-81-5 1-bromo-5-methoxy-4-(1-methylethoxy)-2-[[[2-[4-(1-ethylethoxy)phenyl]ethyl]thio]methyl]benzene 
• 380375-82-6 1-bromo-5-methoxy-4-(1-methylethoxy)-2-[[2-[4-(1-methylethoxy)phenyl]ethylsulfonyl]methyl]benzene 
• 1072709-04-6 1-(2-bromo-5-isopropoxy-4-methoxyphenyl)ethanol 
• 475161-30-9 1-bromo-4-isopropoxy-2-[4-(4-isopropoxyphenyl)butyl]-5-methoxybenzene 
• 445483-27-2 1-(2-benzylsulfanyl-5-isopropoxy-4-methoxy-phenyl)-3-(3-isopropoxy-4-methoxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-prop-2-yn-1-ol 
• 445483-26-1 1-(2-benzylthio-5-isopropoxy-4-methoxyphenyl)-3-(3-isopropoxy-4-methoxyphenyl)prop-2-yn-1-one 
• 445483-24-9 1-(2-benzylthio-5-isopropoxy-4-methoxyphenyl)-3-(3-isopropoxy-4-methoxyphenyl)prop-2-yn-1-ol 
• 618388-65-1 1-(2-benzylthio-5-isopropoxy-4-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-yn-1-ol 

Relevant academic research and scientific papers

Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold

A new class of topoisomerase I inhibitors containing the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one (abbreviated as BBPI) ring system have been developed based on structure-activity relationship studies of the cytotoxic marine alkaloid la

Total synthesis of the benzo[c]phenanthridine alkaloids, terihanine and isoterihanine, and their antitumor activity

A new total synthesis of terihanine (2a) and isoterihanine (2b) was established by our new bond formation between the C4b and N5 positions of the benzo[c]phenanthridine ring based on a microwave-assisted thermal electrocyclic reaction of 2-cycloalkenylbenzaldoxime as an aza 6π-electron system. In addition, the antitumor activity of these synthesized compounds, including nitidine and nornitidine was evaluated in HCT-116 cells.

Synthesis and evaluation of topoisomerase I inhibitors possessing the 5,13-dihydro-6H-benzo[6,7]indolo[3,2-c]-quinolin-6-one scaffold

Novel topoisomerase I inhibitors possessing the 5,13-dihydro-6H-benzo[6,7]indolo[3,2-c]quinolin-6-one (BIQ) scaffold were designed and synthesized. This scaffold was constructed using sequential and regioselective functionalization of the pyrrole core thr

Thermolytic Synthesis of Naphthalenes via Intramolecular Cyclocondensation of o -Phenylallylbenzaldehydes

The development of intramolecular carbonyl-ene type cyclocondensation of oxygenated o -phenylallylbenzaldehydes in refluxing decalin is reported. The facile and easy-to-operate thermolytic rearrangement procedure generates substituted naphthalenes in good to excellent yields.Georg Thieme Verlag Stuttgart - New York.

Efficient One-Pot Synthesis of Tetrahydronaphtho[2,1-f]isoquinolines by Using Domino Pictet–Spengler/Friedel–Crafts-Type Reactions

This study describes a facile and efficient one-pot method for the synthesis of a tetrahydronaphtho[2,1-f]isoquinoline alkaloid. An N-protected amino aldehyde biaryl substrate underwent domino Pictet–Spengler/Friedel–Crafts-type cyclization reactions to p

NON-STEROIDAL COMPOUNDS

The present invention relates to non-steroidal compounds useful in the treatment of inflammatory conditions and pharmaceutical compositions comprising them. A representative example of these compounds is formula (III).

Novel derivatives and analogues of galanthamin

New compounds of general formula I 1

Iodine-Induced Reaction Cascades for the Rapid Construction of Variously Substituted Benzothiophenes

(Equation presented) Readily accessible propynols with a 2-thioxyphenyl substituent selectively undergo 5-exo-iodocyclization followed by tandem rearrangement and elimination or substitution processes to give selective access to either 2-acyl- or 2-(1-iod

12H-[2]-benzothiepino[6,5a,5-bc]benzofuran: Synthesis of a sulfur-analog of galanthamine

An analog of the anti-Alzheimer drug galanthamine, carrying a SO2-moiety instead of an amino-functionality, has been synthesized as a racemic mixture using tandem cyclization techniques to form a new four membered heterocyclic ring system.

Synthesis and biological activity of some antitumor benzophenanthridinium salts

A facile synthesis of benzophenanthridinium salts was developed and used for preparing a number of these compounds. The antitumor activities in mouse leukemia L1210 (LE) and P388 (PS) were determined as well as some selected antimicrobial activities. Alth