1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Base Information

Chemical Name:1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil
CAS No.:136631-99-7
Molecular Formula:C₁₉H₂₇ClN₂O₄SeSi
Molecular Weight:489.933
Hs Code.:

Synonyms:1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Suppliers and Price of 1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Chemical Property:

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Technology Process of 1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

There total 3 articles about 1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 81777-50-6
1-<(2-hydroxyethoxy)methyl>-5-chlorouracil

: 136631-99-7
1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / imidazole / dimethylformamide / Ambient temperature

2: 1.) LDA / 1.) THF, from -78 deg C to -70 deg C, 1 h, 2.) THF, -78 deg C, 30 min

With 1H-imidazole; lithium diisopropyl amide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00115a022

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136631-99-7
1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / imidazole / dimethylformamide / Ambient temperature

2: 1.) LDA / 1.) THF, from -78 deg C to -70 deg C, 1 h, 2.) THF, -78 deg C, 30 min

With 1H-imidazole; lithium diisopropyl amide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00115a022

Reference yield:

: 1666-13-3
diphenyl diselenide

: 121749-96-0
1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-5-chlorouracil

: 136631-99-7
1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylselenenyl)-5-chlorouracil

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, from -78 deg C to -70 deg C, 1 h, 2.) THF, -78 deg C, 30 min;
DOI:10.1021/jm00115a022