1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane

Base Information

• Chemical Name: 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane
• CAS No.: 1581771-57-4
• Molecular Formula: C₂₂H₃₈B₂O₄
• Molecular Weight: 388.163
• Mol file: 1581771-57-4.mol

Synonyms:1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane

Chemical Property of 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane

There total 2 articles about 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + 1,3-dibromoadamantane (876-53-9) + 2,2'-bis(1,3,2-benzodioxaborole) (13826-27-2) → 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane (1581771-57-4)

Guidance literature:

1,3-dibromoadamantane; 2,2'-bis(1,3,2-benzodioxaborole); With tetrabutylammonium tetrafluoroborate; In N,N-dimethyl acetamide; at 25 ℃; for 0.316667h; Electrolysis; Inert atmosphere;

2,3-dimethyl-2,3-butane diol; With triethylamine; In N,N-dimethyl acetamide; at 25 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jacs.1c06473

Reference yield:

1,3-dibromoadamantane (876-53-9) + bis(pinacol)diborane (73183-34-3) → 1,3-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)adamantane (1581771-57-4)

Guidance literature:

bis(pinacol)diborane; With potassium tert-butylate; [1,3-bis(2,4,6-trimethylphenyl)imidazol]-2-ylidene; zinc(II) chloride; In tert-butyl methyl ether; for 0.5h; Inert atmosphere; Schlenk technique; Glovebox;

1,3-dibromoadamantane; In tert-butyl methyl ether; at 20 ℃; for 4h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/anie.201308855

upstream raw materials:

1,3-dibromoadamantane

bis(pinacol)diborane

2,3-dimethyl-2,3-butane diol

2,2'-bis(1,3,2-benzodioxaborole)