(1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

Base Information

Chemical Name:(1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide
CAS No.:1258445-97-4
Molecular Formula:C₂₅H₂₄F₅N₅O₄S
Molecular Weight:585.555
Hs Code.:

(1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

Synonyms:(1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

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Technology Process of (1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

There total 1 articles about (1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 1258445-91-8
(1R,2R,4R)-4-(4-bromo-2-trifluoromethylbenzenesulfonyl)-2-(3,3-difluoroazetidine-1-carbonyl)cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

: 761446-44-0
1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 1258445-97-4
(1R,2R,4R)-2-(3,3-difluoroazetidine-1-carbonyl)-4-[4-(1-methyl-1H-pyrazol-4-yl)-2-trifluoromethylbenzenesulfonyl]cyclopentanecarboxylic acid (1-cyanocyclopropyl)amide

Guidance literature:: With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 80 ℃; for 2h; Inert atmosphere;