methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Base Information

Chemical Name:methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate
CAS No.:1232168-21-6
Molecular Formula:C₂₀H₂₁NO₄S
Molecular Weight:371.457
Hs Code.:

Synonyms:methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Suppliers and Price of methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Chemical Property:

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Technology Process of methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

There total 3 articles about methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 51220-86-1,149703-21-9,42384-33-8
N-(p-toluenesulfonyl)-L-phenylalanine methyl ester

: 106-96-7
propargyl bromide

: 1232168-21-6
methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; In acetonitrile; at 20 ℃; for 47h; Inert atmosphere;
DOI:10.1021/ol101034s

Reference yield:

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 1232168-21-6
methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane

2: potassium carbonate / dichloromethane

With pyridine; potassium carbonate; In dichloromethane;
DOI:10.1021/acs.orglett.0c01685

Reference yield:

: 70-55-3
toluene-4-sulfonamide

: 1232168-21-6
methyl (2S)-2-{N-(prop-2-ynyl)-4-toluenesulfonamido}-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane

2: potassium carbonate / dichloromethane

With pyridine; potassium carbonate; In dichloromethane;
DOI:10.1021/acs.orglett.0c01685