1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione

Base Information

Chemical Name:1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione
CAS No.:115084-81-6
Molecular Formula:C₈H₁₃NO₂
Molecular Weight:155.197
Hs Code.:
European Community (EC) Number:856-875-1
DSSTox Substance ID:DTXSID101242539
Mol file:115084-81-6.mol

Synonyms:115084-81-6;1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione;2,4-Pyrrolidinedione,1-methyl-5-(1-methylethyl)-(9CI);SCHEMBL21939671;DTXSID101242539;1-methyl-5-(propan-2-yl)pyrrolidine-2,4-dione;EN300-3469496;1-Methyl-5-(1-methylethyl)-2,4-pyrrolidinedione

Suppliers and Price of 1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione

Chemical Property:

Boiling Point:285.7±33.0 °C(Predicted)
PKA:12.78±0.40(Predicted)
PSA：37.38000
Density:1.071±0.06 g/cm3(Predicted)
LogP:0.38010
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:155.094628657
Heavy Atom Count:11
Complexity:198

Purity/Quality:: 99.0%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1C(=O)CC(=O)N1C

Technology Process of 1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione

There total 3 articles about 1-Methyl-5-propan-2-ylpyrrolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42417-65-2
Z-MeVal-OH

: 115084-81-6
1-methyl-5-isopropylpyrrolidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / methanol / 4 h / Heating

2: 70 percent / DCC / CH₂Cl₂

3: 1.) NaOMe / 1.) MeOH, 2.) MeCN, reflux, 8h

With sodium methylate; dicyclohexyl-carbodiimide; In methanol; dichloromethane;
DOI:10.1016/S0040-4039(00)86248-6

Reference yield:

: 35016-37-6,769890-37-1
N-methyl-L-valine methyl ester

: 115084-81-6
1-methyl-5-isopropylpyrrolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / DCC / CH₂Cl₂

2: 1.) NaOMe / 1.) MeOH, 2.) MeCN, reflux, 8h

With sodium methylate; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1016/S0040-4039(00)86248-6

Reference yield:

: 88517-58-2
(S)-2-[(2-Ethoxycarbonyl-acetyl)-methyl-amino]-3-methyl-butyric acid methyl ester

: 115084-81-6
1-methyl-5-isopropylpyrrolidine-2,4-dione

Guidance literature:: With sodium methylate; Yield given. Multistep reaction; 1.) MeOH, 2.) MeCN, reflux, 8h;
DOI:10.1016/S0040-4039(00)86248-6