5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one

Base Information

Chemical Name:5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one
CAS No.:115012-10-7
Molecular Formula:C₇H₆N₂O₂
Molecular Weight:150.137
Hs Code.:
DSSTox Substance ID:DTXSID40552730
Mol file:115012-10-7.mol

Synonyms:115012-10-7;5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one;5-hydroxy-5,6-dihydropyrrolo[3,4-b]pyridin-7-one;7H-Pyrrolo[3,4-b]pyridin-7-one,5,6-dihydro-5-hydroxy-(9CI);DTXSID40552730;5-Hydroxy-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one

Suppliers and Price of 5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5,6-dihydro-5-hydroxy-7H-Pyrrolo[3,4-b]pyridin-7-one 97.00%
5G
$ 1700.00

AccelPharmtech
5,6-dihydro-5-hydroxy-7H-Pyrrolo[3,4-b]pyridin-7-one 97.00%
1G
$ 1530.00

Total 3 raw suppliers

Chemical Property of 5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one

Chemical Property:

PSA：62.22000
LogP:0.14470
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:150.042927438
Heavy Atom Count:11
Complexity:183

Purity/Quality:

98%min ^*data from raw suppliers

5,6-dihydro-5-hydroxy-7H-Pyrrolo[3,4-b]pyridin-7-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=O)NC2O)N=C1

Technology Process of 5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one

There total 2 articles about 5-hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.1%

: 4664-00-0,303983-78-0
2,3-pyridinedicarboximide

: 115012-09-4
6,7-Dihydro-7-hydroxy-5H-pyrrolo<3,4-b>pyridin-5-one

: 115012-10-7
5,6-dihydro-5-hydroxy-7H-pyrrolo<3,4-b>pyridin-7-one

Guidance literature:: With sodium tetrahydroborate; In methanol; chloroform; at -20 ℃; for 30h;
DOI:10.1246/bcsj.60.4178

Reference yield:

: 89-00-9
Pyridine-2,3-dicarboxylic acid

: 115012-09-4
6,7-Dihydro-7-hydroxy-5H-pyrrolo<3,4-b>pyridin-5-one

: 115012-10-7
5,6-dihydro-5-hydroxy-7H-pyrrolo<3,4-b>pyridin-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetamide; acetic anhydride / Reflux

2: sodium tetrahydroborate / chloroform; methanol / -20 °C

With acetamide; sodium tetrahydroborate; acetic anhydride; In methanol; chloroform;
DOI:10.1039/c6cc02002j