115012-09-4

Basic information

• Product Name: 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)
• Synonyms: 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI);7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
• CAS NO: 115012-09-4
• Molecular Formula: C₇H₆N₂O₂
• Molecular Weight: 150.136
• Product Categories: PYRROLIDINE;PYRIDINE
• Mol File: 115012-09-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)(115012-09-4)
• EPA Substance Registry System: 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI)(115012-09-4)

Safety Data

• Hazardous Substances Data: 115012-09-4(Hazardous Substances Data)

Usage

General Description

5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) is a chemical compound with the molecular formula C8H7NO2. It is a pyrrolopyridine derivative that contains a pyridine ring fused to a pyrrole ring. 5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-7-hydroxy-(9CI) is classified as a pyridone and is known for its biological and pharmacological activities. It has been studied for its potential use in drug development due to its ability to interact with biological systems, particularly as an inhibitor or activator of specific enzymes. It is also used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. The compound is commonly used in research settings to study its pharmacological properties and potential therapeutic applications.

Upstream product

• 4664-00-0 2,3-pyridinedicarboximide 
• 89-00-9 Pyridine-2,3-dicarboxylic acid 

Downstream Products

• 135128-27-7 7-(4-Bromo-phenyl)-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 135128-26-6 7-(2-Bromo-phenyl)-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 135128-25-5 7-(4-Methoxy-phenyl)-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 135128-20-0 7-(2,5-Dimethoxy-phenyl)-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 132033-48-8 6,7-Dihydro-7-phenyl-5H-pyrrolo<3,4-b>pyridin-5-one 
• 132033-58-0 4b-Phenyl-5,10-dihydro-4bH-4,10a-diaza-benzo[b]fluoren-11-one 
• 132033-57-9 10a-Phenyl-8,9,10,10a-tetrahydro-7H-pyrido[2,3-a]indolizin-5-one 
• 132033-56-8 9a-Phenyl-7,8,9,9a-tetrahydro-pyrido[2,3-a]pyrrolizin-5-one 
• 5657-51-2 7H-furo[3,4-b]pyridin-5-one 
• 135128-43-7 6,7-dihydro-7-phenylsulfonyl-5H-pyrrolo<3,4-b>pyridin-5-one 
• 135128-42-6 6,7-dihydro-7-(p-tolylthio)-5H-pyrrolo<3,4-b>pyridin-5-one 
• 115012-14-1 6,7-dihydro-7-amino-5H-pyrrolo<3,4-b>pyridin-5-one 
• 40107-93-5 6,7-dihydro-5H-pyrrolo<3,4-b>pyridin-5-one 
• 115012-11-8 2-(hydroxymethyl)nicotinamide 

Relevant articles and documents

The Thermally-Controlled Chemoselective Reduction of 5H-Pyrrolopyridine-5,7(6H)-dione with Sodium Borohydride

The title reaction produced either 2-(hydroxymethyl)nicotinamide or 6,7-dihydro-7-hydroxy-5H-pyrrolopyridin-5-one as the major product at room temperature or -20 deg C, respectively, along with the corresponding regioisomers as minor products.These novel compounds were converted to known compounds in order to establish their isomeric structures.

Pyridine salt / 1,4-dihydropyridine derivative and preparation method thereof

The present invention discloses a pyridine salt / 1,4-dihydropyridine derivative (NAD / NADH analog) with novel structure. The NAD / NADH analog can substitute natural NAD / NADH to be applied to a biochemical system for redox reactions, and can also be used as an electron carrier for the energy transfer of an enzymatic fuel cell. Further, the NAD / NADH analogs provided by the invention are easy to prepare, isolate and purify, and have a high yield.

Magnesium Ion Assisted Highly Regio- and Chemoselective Reduction of 5H-Pyrrolopyridine-5,7(6H)-diones with Sodium Borohydride. A Convenient Synthesis of 6,7-Dihydro-7-hydroxy-5H-pyrrolopyridin-5-ones

6-Substituted and unsubstituted 6,7-dihydro-7-hydroxy-5H-pyrrolopyridin-5-ones were predominantly obtained in excellent yield by the reduction of the corresponding 5,7-diones with sodium borohydride in the presence of Mg ion at 0 deg C.The highly r