tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

Base Information

Chemical Name:tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate
CAS No.:442913-30-6
Molecular Formula:C₂₃H₂₇NO₃
Molecular Weight:365.472
Hs Code.:

Synonyms:tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

Suppliers and Price of tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

There total 1 articles about tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 81477-94-3
N-(diphenylmethylene)glycine tert-butyl ester

: 99700-70-6
(S)-(-)-4-iodo-1,2-epoxybutane

: 442913-30-6
tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

Guidance literature:: 9-anthracenylmethyl-chinchonidinium bromide; at -60 ℃; for 18h;
DOI:10.1002/hlca.200290026

Reference yield: 98.0%

: 103-67-3
benzyl-methyl-amine

: 442913-30-6
tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

: 442913-31-7
tert-butyl (2S,5S)-2-[(1,1-diphenylmethylidene)amino]-5-hydroxy-6-[methyl(phenylmethyl)amino]hexanoate

Guidance literature:: In methanol; at 20 ℃; for 13h;
DOI:10.1021/ol026101e DOI:10.1002/hlca.200290026

Reference yield:

: 442913-30-6
tert-butyl (2S)-2-[(1,1-diphenylmethylidene)amino]-4-[(2S)-oxiran-2-yl]butanoate

: 442913-34-0
(3S,6S)-6-[((2R,3R,4R,5R,6E)-5-{[(tert-butyl)dimethylsilyl]oxy}-3-hydroxy-2-methoxy-8-methyl-4-(phenylmethoxy)non-6-enoyl)amino]-2,3,4,5,6,7-hexahydro-1-methyl-7-oxoazepin-3-yl acetate

Guidance literature:: Multi-step reaction with 6 steps

1: 98 percent / methanol / 13 h / 20 °C

2: 86 percent / citric acid; water / tetrahydrofuran / 0.5 h / 20 °C

3: 0.39 g / H₂ / Pearlman's catalyst / ethanol / 11 h

4: 88 percent / NaOMe / methanol / 1.5 h / 85 °C

5: 82 percent / TFA / 20 °C

6: 94 percent / dioxane / 18 h / Heating

With water; hydrogen; sodium methylate; trifluoroacetic acid; citric acid; palladium dihydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol;
DOI:10.1002/hlca.200290026