N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Base Information

Chemical Name:N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester
CAS No.:1321826-37-2
Molecular Formula:C₅₈H₆₆F₂N₂O₁₃
Molecular Weight:1037.16
Hs Code.:

N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Synonyms:N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Suppliers and Price of N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

There total 4 articles about N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1240035-65-7
3,4,6-tri-O-benzyl-2-fluoro-2-deoxy-α-D-galactopyranosyl trichloroacetimidate

: 1191118-09-8
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: 1321826-37-2
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Guidance literature:: 3,4,6-tri-O-benzyl-2-fluoro-2-deoxy-α-D-galactopyranosyl trichloroacetimidate; N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-α-D-galactopyranosyl)-L-threonine tert-butyl ester; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere; Molecular sieve;

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 20h; optical yield given as %de; Molecular sieve; Inert atmosphere;
DOI:10.1039/c1ob05373f

Reference yield:

: 1321826-32-7
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2-deoxy-3,4-isopropylidene-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: 1321826-37-2
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2,4,6-trimethyl-pyridine; diethylamino-sulfur trifluoride / dichloromethane / 1 h / 80 °C / Microwave irradiation

2.1: methanol / 14 h / 20 °C

3.1: dichloromethane / 1 h / 20 °C / Inert atmosphere; Molecular sieve

3.2: 20 h / 0 °C / Molecular sieve; Inert atmosphere

With 2,4,6-trimethyl-pyridine; methanol; diethylamino-sulfur trifluoride; In dichloromethane;
DOI:10.1039/c1ob05373f

Reference yield:

: 1321826-33-8
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3,4-isopropylidene-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: 1321826-37-2
N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

: N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 14 h / 20 °C

2.1: dichloromethane / 1 h / 20 °C / Inert atmosphere; Molecular sieve

2.2: 20 h / 0 °C / Molecular sieve; Inert atmosphere

With methanol; In dichloromethane;
DOI:10.1039/c1ob05373f