(S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide

Base Information

• Chemical Name: (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide
• CAS No.: 109013-66-3
• Molecular Formula: Br*C₁₆H₁₆N₃O₄
• Molecular Weight: 394.225

Synonyms:(S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide

Chemical Property of (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide

There total 2 articles about (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

S-(+)-7-Methoxycarbonyl-5,6,7,8-tetrahydroimidazo<1,5-c>pyrimidin-5-on (69614-04-6) + α-bromoacetophenone (70-11-1) → (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide (109013-66-3)

Guidance literature:

In acetonitrile; for 6h; Heating;

DOI:10.1021/jo00392a018

Reference yield:

l-histidine methyl ester dihydrochloride (4467-54-3,5619-10-3,7389-87-9,18684-16-7,22888-60-4,32381-17-2,92742-29-5,100009-20-9) → (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide (109013-66-3)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂ / 0.25 h / Heating

2: 95 percent / acetonitrile / 6 h / Heating

In dichloromethane; acetonitrile;

DOI:10.1021/jo00392a018

Reference yield: 99.5%

(S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide (109013-66-3) → 1-(2-oxo-2-phenylethyl)-L-histidine hydrochloride hydrobromide (133807-77-9)

Guidance literature:

With hydrogenchloride; for 4h; Heating;

DOI:10.1002/jhet.5570280118

upstream raw materials:

S-(+)-7-Methoxycarbonyl-5,6,7,8-tetrahydroimidazo<1,5-c>pyrimidin-5-on

α-bromoacetophenone

l-histidine methyl ester dihydrochloride

Downstream raw materials:

1-(2-oxo-2-phenylethyl)-L-histidine hydrochloride hydrobromide

N-(2-propyloxycarbonyl)-1-(2-oxo-2-phenylethyl)-L-histidine, methyl ester

N(α)-benzyloxycarbonyl-N(τ)-phenacyl-L-histidine methyl ester

N-(tert-butoxycarbonyl)-1-(2-oxo-2-phenylethyl)-L-histidine, methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 109013-66-3 (S)-5,6,7,8-tetrahydro-7-(methoxycarbonyl)-2-(2'-oxo-2'-phenylethyl)-5-oxoimidazo<1,5-c>pyrimidinium bromide

Send

Send

Metric Ton KG G Pound L ML

Send

Send