α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Base Information

Chemical Name:α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane
CAS No.:143143-82-2
Molecular Formula:C₃₆H₄₄N₂O₅Si
Molecular Weight:612.841
Hs Code.:

Synonyms:α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Suppliers and Price of α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

There total 8 articles about α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 103-71-9
phenyl isocyanate

: 143143-77-5
α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-7-methyl-β-2,α-4-dihydroxy-α-3,7-dimethylbicyclo<4.1.0>heptane

: 143143-82-2
α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Guidance literature:: With pyridine; dmap; In dichloromethane; for 9h; Ambient temperature;
DOI:10.1021/jo00046a017

Reference yield:

: 4028-23-3
Allylchlorodimethylsilane

: 143143-82-2
α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA, HMPA / 1.) THF, r. t., 14 h

2: 55 percent / AlCl₃, LiAlH₄ / diethyl ether; tetrahydrofuran / 6 h / Ambient temperature

3: 85 percent / pyridine, DMAP / CH₂Cl₂ / 9 h / Ambient temperature

With pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium aluminium tetrahydride; aluminium trichloride; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo00046a017

Reference yield:

: 100-39-0
benzyl bromide

: 143143-82-2
α-1-(allyldimethylsilyl)-7-exo-<(benzyloxy)methyl>-β-2,α-4-(dicarbamoyloxy)-α-3,7-dimethylbicyclo<4.1.0>heptane

Guidance literature:: Multi-step reaction with 4 steps

1: 42.2 percent / NaH, n-Bu₄NI / tetrahydrofuran / 3 h

2: 1.) LDA, HMPA / 1.) THF, r. t., 14 h

3: 55 percent / AlCl₃, LiAlH₄ / diethyl ether; tetrahydrofuran / 6 h / Ambient temperature

4: 85 percent / pyridine, DMAP / CH₂Cl₂ / 9 h / Ambient temperature

With pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium aluminium tetrahydride; aluminium trichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo00046a017