5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid

Base Information

Chemical Name:5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid
CAS No.:1078151-34-4
Molecular Formula:C₁₂H₁₈BNO₄S
Molecular Weight:283.156
Hs Code.:
Mol file:1078151-34-4.mol

Synonyms:5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid

Suppliers and Price of 5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronicacid 95+%
1g
$ 772.00

Alichem
(5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronicacid
1g
$ 665.68

Total 7 raw suppliers

Chemical Property of 5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid

Chemical Property:

Boiling Point:474.1±55.0 °C(Predicted)
PKA:8.60±0.20(Predicted)
Density:1.29±0.1 g/cm3(Predicted)
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid

There total 2 articles about 5-(tert-butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 230301-73-2
6,7-dihydro-4H-thieno[3,2-c]-pyridine-5-carboxylic acid tert-butyl ester

5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid: 1078151-34-4
5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid

Guidance literature:: 6,7-dihydro-4H-thieno[3,2-c]-pyridine-5-carboxylic acid tert-butyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; at -65 - -30 ℃; for 2.5h;

With Trimethyl borate; In tetrahydrofuran; at -65 - 10 ℃;

With water; ammonium chloride; In tetrahydrofuran; at 10 ℃; for 0.5h;

Reference yield:

: C₁₈H₃₀BNO₄S

5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid: 1078151-34-4
5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; for 0.333333h;

Reference yield: 79.0%

5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid: 1078151-34-4
5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl-2-boronic acid

⁽⁰⁸¹⁾C₀₇₅₀₆: 1147015-37-9
⁽⁰⁸¹⁾C₀₇₅₀₆

2-{2-[4-(2-methyl-imidazol-1-ylmethyl)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-6,7-dihydro-4H-thieno[3,2-c]pyridine-5-carboxylic acid tert-butyl ester: 1142947-31-6
2-{2-[4-(2-methyl-imidazol-1-ylmethyl)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-6,7-dihydro-4H-thieno[3,2-c]pyridine-5-carboxylic acid tert-butyl ester

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 170 ℃; for 0.5h; Microwave irradiation;