Technology Process of 1-Cyclopentene-1-carboxaldehyde, 3-methyl-, (R)- (9CI)
There total 7 articles about 1-Cyclopentene-1-carboxaldehyde, 3-methyl-, (R)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; TEA; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
DOI:10.1021/ja00222a022
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) hydrogen, 5percent Pd/C / 1.) ethyl acetate/benzene, 50 psi, 14 H; 2.) pyridine, 0-5 deg C; room temperature overnight
2: 81 percent / 10N sodium hydroxide / methanol / 1 h / Heating
3: 91 percent / periodic acid / tetrahydrofuran / 1.) 0 deg C, 10 min; 2.) room temperature, 1 h
4: 1.) piperidine 2.) glacial acetic acid / 1.) ether, 0 deg C, 2.5 h; 2.) ether, 0 deg C, room temperature 3 h
With
piperidine; sodium hydroxide; palladium on activated charcoal; hydrogen; acetic acid; periodic acid;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja00222a035
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 81 percent / 10N sodium hydroxide / methanol / 1 h / Heating
2: 91 percent / periodic acid / tetrahydrofuran / 1.) 0 deg C, 10 min; 2.) room temperature, 1 h
3: 1.) piperidine 2.) glacial acetic acid / 1.) ether, 0 deg C, 2.5 h; 2.) ether, 0 deg C, room temperature 3 h
With
piperidine; sodium hydroxide; acetic acid; periodic acid;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja00222a035
