(R)-2-Amino-2-ethylhexanoic acid

Base Information

Chemical Name:(R)-2-Amino-2-ethylhexanoic acid
CAS No.:114781-14-5
Molecular Formula:C₈H₁₇NO₂
Molecular Weight:159.228
Hs Code.:2922498590
DSSTox Substance ID:DTXSID30921496
Nikkaji Number:J655.277C
Mol file:114781-14-5.mol

Synonyms:114781-14-5;(R)-2-Amino-2-ethylhexanoic acid;(2R)-2-AMINO-2-ETHYLHEXANOIC ACID;D-Norleucine, 2-ethyl-;(R)-2-amino-2-ethyl hexanoic acid;MFCD05663537;2-Ethylnorleucine;(2R)-2-Amino-2-ethyl-hexanoic acid;2-Ethyl-D-norleucine;SCHEMBL7465019;DTXSID30921496;QUDXVGQYPUXXER-MRVPVSSYSA-N;AKOS006294447;D78555

Suppliers and Price of (R)-2-Amino-2-ethylhexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-2-AMINO-2-ETHYLHEXANOIC ACID 95.00%
5MG
$ 501.63

Total 1 raw suppliers

Chemical Property of (R)-2-Amino-2-ethylhexanoic acid

Chemical Property:

PSA：63.32000
LogP:2.06900
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:159.125928785
Heavy Atom Count:11
Complexity:136

Purity/Quality:: (R)-2-AMINO-2-ETHYLHEXANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(CC)(C(=O)O)N
Isomeric SMILES:CCCC[C@](CC)(C(=O)O)N

Technology Process of (R)-2-Amino-2-ethylhexanoic acid

There total 9 articles about (R)-2-Amino-2-ethylhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 152802-65-8
(+/-)-ethyl 2-amino-2-ethylhexanoate

: 114781-14-5
(R)-2-amino-2-ethylhexanoic acid

: 164262-42-4
ethyl (S)-2-amino-2-ethylhexanoate

Guidance literature:: With porcine liver esterase; In phosphate buffer; at 30 ℃; for 7.5h; pH=8.0;
DOI:10.1002/1522-2675(20001004)83:10<2823::AID-HLCA2823>3.0.CO;2-#

Reference yield:

: 6300-78-3
2-Amino-2-ethyl-hexanoic acid

: 114781-14-5
(R)-2-amino-2-ethylhexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂SO₄ / Heating

2: porcine liver esterase / aq. phosphate buffer / 7.5 h / 30 °C / pH 8.0

With porcine liver esterase; sulfuric acid; In phosphate buffer; 1: Esterification / 2: Hydrolysis;
DOI:10.1002/1522-2675(20001004)83:10<2823::AID-HLCA2823>3.0.CO;2-#

Reference yield:

: 106-35-4
heptan-3-one

: 114781-14-5
(R)-2-amino-2-ethylhexanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: NH₄Cl / H₂O; ethanol / 48 h / 55 - 60 °C

2: conc. HCl / 24 h / 80 °C

3: H₂SO₄ / Heating

4: porcine liver esterase / aq. phosphate buffer / 7.5 h / 30 °C / pH 8.0

With hydrogenchloride; porcine liver esterase; sulfuric acid; ammonium chloride; In phosphate buffer; ethanol; water; 1: Condensation / 2: Hydrolysis / 3: Esterification / 4: Hydrolysis;
DOI:10.1002/1522-2675(20001004)83:10<2823::AID-HLCA2823>3.0.CO;2-#