ETHYL 2-AMINO-2-ETHYLHEXANOATE

Base Information

• Chemical Name: ETHYL 2-AMINO-2-ETHYLHEXANOATE
• CAS No.: 152802-65-8
• Molecular Formula: C10H21 N O2
• Molecular Weight: 187.282
• Hs Code.: 2922499990
• Mol file: 152802-65-8.mol

Synonyms:DL-Norleucine,2-ethyl-, ethyl ester; Ethyl 2-amino-2-ethylhexanoate

Chemical Property of ETHYL 2-AMINO-2-ETHYLHEXANOATE

Chemical Property:

• Vapor Pressure: 0.058mmHg at 25°C
• Refractive Index: 1.446
• Boiling Point: 232.8°C at 760 mmHg
• Flash Point: 99.4°C
• PSA: 52.32000
• Density: 0.932g/cm³
• LogP: 2.54750
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-Amino-2-ethylhexanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-AMINO-2-ETHYLHEXANOATE

There total 8 articles about ETHYL 2-AMINO-2-ETHYLHEXANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

ethyl 2-(benzylideneamino)-2-ethylhexanoate (152802-64-7) → (+/-)-ethyl 2-amino-2-ethylhexanoate (152802-65-8)

Guidance literature:

With hydrogenchloride; for 1h; Ambient temperature;

Reference yield: 80.0%

(+/-)-ethyl 2-benzylideneamino-2-ethylhexanoate → (+/-)-ethyl 2-amino-2-ethylhexanoate (152802-65-8)

Guidance literature:

With hydrogenchloride; In water; Petroleum ether; at 0 - 20 ℃; for 16h;

Reference yield:

ethyl (E)-2-(benzylideneamino)butanoate → (+/-)-ethyl 2-amino-2-ethylhexanoate (152802-65-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C

1.2: 1 h / 20 °C

2.1: hydrogenchloride / water; Petroleum ether / 16 h / 0 - 20 °C

With hydrogenchloride; sodium hydride; In water; N,N-dimethyl-formamide; mineral oil; Petroleum ether;

upstream raw materials:

ethyl 2-(benzylideneamino)-2-ethylhexanoate

ethanol

2-Amino-2-ethyl-hexanoic acid

heptan-3-one

Downstream raw materials:

(S)-2-amino-2-ethylhexanoic acid

(R)-2-amino-2-ethylhexanoic acid

ethyl (S)-2-amino-2-ethylhexanoate

(+/-)-2-amino-2-ethylhexan-1-ol