Technology Process of 1-(4-(diphenylphosphino)phenyl)-2-(dicyclohexylphosphino)-4,5-dimethyl-1H-imidazole
There total 4 articles about 1-(4-(diphenylphosphino)phenyl)-2-(dicyclohexylphosphino)-4,5-dimethyl-1H-imidazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-(4-(diphenylphosphino)phenyl)-4,5-dimethyl-1H-imidazole;
With
lithium diisopropyl amide;
In
diethyl ether;
at -30 - 20 ℃;
Inert atmosphere;
chlorodicyclohexylphosphane;
In
diethyl ether;
at -30 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/om300145d
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium acetate; palladium diacetate / ISOPROPYLAMIDE / 3 h / 130 °C / Inert atmosphere
2.1: lithium diisopropyl amide / diethyl ether / -30 - 20 °C / Inert atmosphere
2.2: 2 h / -30 - 20 °C / Inert atmosphere
With
potassium acetate; palladium diacetate; lithium diisopropyl amide;
In
diethyl ether; ISOPROPYLAMIDE;
1.1: Stelzer coupling;
DOI:10.1021/om300145d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonium chloride / Inert atmosphere
2.1: potassium acetate; palladium diacetate / ISOPROPYLAMIDE / 3 h / 130 °C / Inert atmosphere
3.1: lithium diisopropyl amide / diethyl ether / -30 - 20 °C / Inert atmosphere
3.2: 2 h / -30 - 20 °C / Inert atmosphere
With
potassium acetate; palladium diacetate; ammonium chloride; lithium diisopropyl amide;
In
diethyl ether; ISOPROPYLAMIDE;
2.1: Stelzer coupling;
DOI:10.1021/om300145d